摘要
目的:探讨丹参佐治毛细支气管炎的疗效及其可能的机理。方法:73例毛细支气管患儿随机分为常规组和丹参组,均用常规方法治疗,但后者加用复方丹参静脉滴注。在治疗前、后用全自动散射比浊法测定并比较两组患儿血清IgE、IgG、IgA、补体C3和C4水平。结果:丹参组和常规组总有效率依次为94.44%和78.38%,差异具有统计学意义(P<0.05)。治疗后,丹参组患者血清IgE、C3和C4水平下降,IgG、IgA水平上升,与治疗前相比均有一定程度差异(P<0.01-0.05)。治疗后,常规组患者仅IgE水平下降(P<0.01),但其余指标与治疗前差异无统计学意义(P>0.05)。结论:丹参佐治毛细支气管炎,临床效果较好,且可调节机体的体液免疫应答,增强机体的抗感染能力。
Objective： To observe the effects of salvia miltiorrhiza in treatment of children with bronchiolitis and its possible roles in humoral immunological regulation. Methods： Seventy-three children with bronchiolitis were divided into routine group and salvia mil- tiorrhiza group. Both were treated with routine methods, including of anti-infection, dissipating phlegm, stopping cough, giving oxygen, fluid infusion and etc, but the patients in salvia miltiorrhiza group were administered additionally to salvia miltiorrhiza. The levels of IgE, IgG, IgA, C3 and C4 were detected with automatic nephelometry before and after treatment in the two groups. Results： The total effective rates of the two groups were 94.44% and 78.38% respectively, with significant difference （P〈0.05）. After treatment, the levels of IgE, C3 and C4 decreased but the levels of IgG and IgA increased in salvia miltiorrhiza group, which were significantly different with those before treatment （P〈0.01-0.05）. Compared with those before treatment, only the level of IgE decreased in routine group after treatment （P〈0.01）, the levels of IgG, IgA, C3 and C4 changed a little without statistical difference. Conclusion： The immunity in patients with bronchiolitis was abnormal. Salvia miltiorrhiza has good effects on bronchiolitis, it can regulate humoral immunological levels into normals and improve immunity against infection.
出处
《现代生物医学进展》
CAS
2007年第12期1880-1881,共2页
Progress in Modern Biomedicine
关键词
毛细支气管炎
体液免疫
丹参
Bronchiolitis
Humoral immunity
Salvia miltiorrhiza
