摘要
肉苁蓉总甙（ＧＣｓ）可明显增强小鼠红细胞ＳＯＤ活性，降低血清ＭＤＡ含量，提高肝、肾组织中ＤＮＡ，ＲＮＡ含量，能明显促进受６０Ｃｏ照射损伤后小鼠红细胞ＳＯＤ活性及脾核酸含量的恢复，降低肝ＭＤＡ含量，提示ＧＣｓ对核酸的保护作用及辐射防护作用与其抗脂质过氧化作用密切相关。
The results showed that oral administration of GCs could markedly increase the activity of SOD in red blood cells as well as the contents of nucleic acid (DNA and RNA) in liver and kidney, decrease the contents of MDA in serum, markedly increase the activity of SOD in red blood cells as well as the contents of nucleic acid in the spleen of mice radio induced by 60 Co, and also lower the contents of MDA in liver. The results suggest that the protective effect of GCs on nucleic acid and antiradiative action may be related to its antilipid peroxidation.
出处
《中国中药杂志》
CAS
CSCD
北大核心
1997年第6期364-367,共4页
China Journal of Chinese Materia Medica
基金
国家中医药管理局科研基金
