摘要
目的探讨PSA检测在慢性前列腺炎（CP）临床分型的确定和治疗效果预测中的意义和应用价值。方法对本院2006年3月至2007年5月门诊诊治的122例CP患者按NIH1995年的分类标准进行分型,分别在治疗前和治疗4～6周后检测T-PSA水平,并设正常对照组。通过对各型CP患者T-PSA水平、以及治疗前后T-PSA的比较,进行统计学分析,以获得相关数据。结果（1）CP的PSA水平均较正常对照组有显著升高;Ⅱ型与ⅢB型之间的T-PSA存在差异,Ⅱ型与ⅢA型之间无明显差异;（2）Ⅱ型治疗前后PSA水平有显著差异,Ⅲ型治疗前后PSA无差异。（3）CP治疗后疗效显著者,PSA水平会有显著下降而一般疗效和无效者,治疗前后PSA无变化。结论血清PSA水平在区分Ⅱ型与ⅢB型CP时,有一定程度的指导意义。但界定值的确定,尚待进一步研究。治疗后PSA是否下降,可能成为一个判断CP治疗有效性的参考标准。
Objective To explore the significance of Prostate-specific antigen test in chronic prostatitis （CP） typing and effect prediction. Methods 122 chronic prostatitis out-patients in local hospital from March 2006 to May 2007 were typed according to 1995 NIH-CPSI. T-PSA was tested pretherapy and post-treatment individually and normal control was set. All T-PSA level of patients were compared and analyzed statistically to gain the data pretherapy and post-treatment. Results （1） T-PSA of CP was higher significantly than normal control. PSA level of type Ⅱ was different from type ⅢB, Type Ⅱ was not different from type ⅢA; （2） PSA level of type Ⅱ prethrapy was great different and type Ⅲ was not different from prethrapy to post-treatment. （3） PSA level was decreased significantly in those with good therapeutic effect of CP and no change was found in those with noneffect or poor therapeutic effect. Conclusion PSA level of serum can distinguish CP of type Ⅱ from type ⅢB in certain extent, but critical value is needed to study further. Perhaps decreasing of PSA level may become the objective criterion of CP therapeutic effect after treatment.
出处
《中国男科学杂志》
CAS
CSCD
2007年第10期55-57,59,共4页
Chinese Journal of Andrology
