摘要
用放射分析法检测３０例急性白血病细胞胰岛素受体（ＩＮＳＲ），其中急性非淋巴细胞白血病２６例，急性淋巴细胞白血病４例。治疗前所有患者细胞膜ＩＮＳＲ数均高于正常对照，完全缓解者明显降低，未缓解者持续增高，甚至高于治疗前。完全缓解者ＩＮＳＲ稍有下降仍高于正常对照者于短期内复发。
The insulin receptor (INSR) on leukemic cells from 30 cases of acute leukemia (including 26 nonlymphocytic and 4 lymphocytic cases) were studied by radioassay. Compared with normal controls, the number of INSR on leukemic cells was markedly increased before treatment. The elevated INSR decreased significantly in complete remission (CR) patients. The INSR remained high or even higher in non remission cases. The CR cases with INSR slightly decreased but still over expressed were prone to early relapse. Hence, the INSR has prognostic significance in acute leukemia.
出处
《白血病》
1997年第1期17-19,共3页
关键词
急性
白血病
胰岛素受体
预后
Acute leukemia Insulin receptor Prognosis
