摘要
患者主因"左侧头痛伴鼻堵一个月"入院,临床明确诊断为"鼻咽腺样囊性癌"。半年前曾于外院行普通外照射放疗DT:200cGy/次×17次及头部伽玛刀治疗,中心剂量:35.6GY,目前局部病灶复发。入院后给与DDP+THP+FUDR全身化疗一周期,症状缓解不明显。另行局部X-刀治疗,已治疗400cGy/次×5次,疼痛症状较前略缓解。本次病例讨论将从病理、影像、手术及放化疗等多方面入手,拟在制定规范的治疗方案,以期减轻患者痛苦,提高生存质量,并指导今后的临床治疗。鼻咽原发性腺样囊性癌比较少见,患者以女性为多见,肿瘤生长呈明显的侵袭性。由于鼻咽部解剖结构复杂,且腺样囊性癌常侵及血管和神经,因此不宜采取手术治疗,而以放疗为首选,其5年的局部控制率及生存率分别为:21%和31%。
The patient was admitted with left-sided headache accompanied by rhinocleisis that persisted for a month. The patient was diagnosed with adenoid cystic carcinoma of the nasopharynx. Six months previously, the patient had been treated with standard radiotherapy （DT： 200cGy, 17 times） and gamma knife （35.6Gy）, but the tumor recurred, prompting this admission. After admission, the patient was given systematic chemotherapy with DDP＋THP＋FUDR for a week, but the symptoms were not relieved. Local gamma knife was applied （400cGy, 5 times） and the pain was slightly relieved. We discuss the pathology, image features, surgery, radiotherapy and chemotherapy of this disease and establish a standard treatment plan. Nasopharynx primary adenoid cystic carcinoma is rare. It appears as an invasive growth and mostly occurs in women. Due to the complicated structure of the nasopharynx and the cancer＇s tendency to invade vessels and nerves, radiotherapy is preferred over surgery. The 5-year local control rate and survival rate are 21% and 31%, respectively.
出处
《中国肿瘤临床》
CAS
CSCD
北大核心
2007年第21期1241-1243,共3页
Chinese Journal of Clinical Oncology
关键词
腺样囊性癌
规范治疗
预后
Adenoid cystic carcinoma Standard treatment plan
