摘要
目的：探讨乳腺癌患者的发病年龄、组织学特点及雌孕激素受体表达与年龄和淋巴结转移之间的关系。方法：采用冰冻切片、免疫组化直接法对乳腺癌组织中雌孕激素受体的分布进行了检测；并对乳腺癌根治术标本进行常规病理组织学观察。结果：８８例乳腺癌患者的临床资料分析发现其发病年龄有两个高峰组，一是４０～４４岁，另一个是５５～５９岁，以第一个高峰组为主，占总例数的２３８６％。对其中３３例乳腺癌新鲜组织雌孕激素受体检测结果是２０例（６０６０％）雌激素受体阳性，１９例（５７５８％）孕激素受体阳性，１６例（４８４８％）二受体同时阳性。分组研究显示＜４５岁与≥４５岁两年龄组雌孕激素受体阳性表达无显著差异性，有淋巴结转移与无淋巴结转移两组间雌孕激素受体阳性表达无显著性差异。结论：乳腺癌的雌孕激素受体阳性表达与患者年龄及淋巴结转移无关。
Objective:To evaluate the high incidence age,histopathology and the correlation between age,lymphonode metastasis and the positive reaction of estrogen and progesterone receptor of breast cancer.Methods:Immunohistochemical direct method in new tissues was used to examine estrogen and progesterone receptor.Results:Patients with breast cancer had two high incidence age classes (40～44 and 55～59 years old).Of all 33 cases,estrogen receptor showed positive in 20 cases (60 60%),Progesterone receptor showred positive in 19 cases (57 58%),both estrogen receptor and progesterone recepter showed positive in 16 cases (48 48%).It was indicated that there was no significant difference of positive show of receptors between <45-year-group and ≥45-year-group,and there was no significant difference between lymphonode metastasis group and non-lymphonode group.Conclusions:There was no correlation between the positive rate of estrogen and progesterone receptor and the age of patient and lymphonode metastasis.
出处
《中国冶金工业医学杂志》
1997年第3期134-136,共3页
Chinese Medical Journal of Metallurgical industry
关键词
乳腺肿瘤
病理
雌激素受体
孕激素受体
免疫组化
Breast cancer/pathology
Estrogen and progesterone receptor
Immunohistochemical method
