摘要
目的了解血清尿酸、胆红素浓度对冠心病的临床意义。方法对156例疑似冠心病患者进行冠状动脉造影术。将其分为冠心病组（81例）和对照组（75例），冠心病组分为单支、双支、三支痛变亚组。分别测定其血清总胆红素、直接胆红素、间接胆红素、尿酸的浓度。结果冠心病组血清总胆红素、间接胆红素显著低于对照组（P〈0．01）；冠心病组血清尿酸明显高于对照组（P〈0．001）；随着冠状动脉病变支数增加血清尿酸明显增加（P〈0．05或P〈0．001）；双支、三支病变组血清总胆红素均低于单支病变组（P〈0．05），而双支与三支病变组血清总胆红素之间无显著性差异。结论血清尿酸浓度升高和胆红素浓度降低与冠心病有着较大的关系，具有一定的临床意义，早期检测有助于预防心血管病的发生和发展。
Objective Understanding of serum uric acid and bilirubin concentration on coronary heart disease and its clinical significance. Methods Take 156 patients with suspected coronary heart disease patients with coronary angiography. The patients were divided to CHD group （81 cases） and the control group （75 cases）, coronary heart disease group was divided into single - , double - , three lesions subgroups. Serum total bilirubin, direct bilirubin, and indirect bilirubin, uric acid concentrations were measured . Results Serum total bilirubin, indirect bilirubin in CHD was significantly lower than that in the control group （ P 〈 0.01 ） ; Serum uric acid in CHD group was higher （ P 〈 0.001 ） ; With the increase in the number of coronary lesions, serum uric acid significantly increased （ P 〈 0.05 or P 〈 0. 001 ） ; double - , In three lesions group, serum total bilirubin were lower than single - vessel disease group （ P 〈 0.05 ） , while there was no significant difference between two - and three- vessel group on serum total bilirubin. Conclusion Elevated serum uric acid concentration and decreased bilirubin concentration heart disease have more relations with CHD. Early detection can help prevent the occurrence and development of cardiovascular disease.
关键词
冠心病
尿酸
胆红素
Coronary heart disease Uric acid Bilirubin
