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彭泽贝母中二萜类成分 被引量:2

Diterpenoids from bulbus of Fritillaria monanth
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摘要 为了研究彭泽贝母的化学成分。利用多种柱色谱方法进行分离纯化,根据光谱数据和理化性质进行结构鉴定。共分离并鉴定了6个对映-贝壳杉类二萜化合物:ent-kauran-15-en-17-ol(I),ent-kauran-15-en-3α,17-diol(II),鄂贝新醇(III),ent-kauran-16α,17-diol(IV),ent-kauran-3α,16α,17-triol(V),ent-16,17-epoxy-kauran-3α-ol(VI)。6个化合物均为首次从彭泽贝母中分得,其中ent-16,17-epoxy-kauran-3α-ol(VI)为新化合物。 To study the chemical constituents of Vrittllaria monanttt Migo, tne constituents wetc separated and purified by column chromatography on silica gel, and the structures were identified by NMR, MS spectral data. Six compounds were isolated and identified as ent-kauran-15-en-17-ol(I),ent-kauran-15-en-3α,17-diol(II), fritillaziebinol (III),ent-kauran-16α,17-diol(IV),ent-kauran-3α,16α,17-triol(V),ent-16,17-epoxy-kauran-3α-ol(VI). All the compounds were isolated from this plant for the first time, and VI is named as ent-16,17-epoxy-kauran-3α-ol, which is a new compound.
机构地区 江西中医学院
出处 《药学学报》 CAS CSCD 北大核心 2007年第11期1152-1154,共3页 Acta Pharmaceutica Sinica
基金 国家自然科学基金重点项目(30160097).
关键词 彭泽贝母 化学成分 ent-16 17-epoxy-kauran-3α-ol Fritillaria monanth Migo chemical constituents ent-16,17-epoxy-kauran-3α-ol
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参考文献8

  • 1The Jiangxi Institute of Traditional Chinese Medicine. Jiangxi Traditional Chinese Medicine (江西中药) [ M ]. Beijing: People's Medical Publishing House, 1959:83.
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二级参考文献4

  • 1汪丽燕,韩传环,王萍,倪光玉,徐叔云.安徽贝母药理作用的实验研究[J]中国药理学通报,1988(06).
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