摘要
目的：观察七氟烷用于儿童患者时的诱导和苏醒特征,评估其安全性和麻醉效果。方法：选择40例符合入选标准的患儿,在全麻下行择期手术。所用患儿均不给术前药,入手术室后面罩直接吸纯氧（1L/min）加七氟烷,逐步升高七氟烷的吸入浓度（最大浓度为7%）,直至患儿睫毛反射消失,维持浓度控制在4.0%以下。所有患儿均行气管插管,可合用维库溴胺0.1mg/kg保证肌松。结果：七氟烷吸入诱导成功率100%,睫毛反射消失时间在60～132s之间;呼吸道分泌物少,气道耐受性好,术中维持浓度为1.0%～4.0%,麻醉效果满意;血流动力学稳定,无心率减慢、血压下降者;全组患儿体温均正常。结论：七氟烷吸入用于小儿诱导快速,气道刺激小,心血管抑制轻,苏醒迅速,麻醉满意,安全可控。
Objective To observe the effect of sevoflurane on the induction and maintenance of anaesthesia in children, and to evaluate its safety and effectiveness. Methods Forty child patients who conformed to the selection standard were operated under anaesthesia with intubation. Without premedicant, all the patients inhaled 100% oxygen（ 1 L/min ） and sevoflurane by mask, and escalated the concentration of sevoflurane （ to the maximum concentration 7 % ） until the lash reflex disappeared, and the maintenance concentration was controlled under 4 %. All the patients were intubated, together with vecuronium 0. 1 mg/kg. Results With little tract excretion, the achievement ratio of induction by sevoflurane was 100% , and the children tolerated well. With stable hemodynamics, 1% ～ 4.0 % maintenance concentration of sevoflurane during the operation showed effective anaesthesia, no decreased heart rate or blood pressure appeared, and all the patients ＇ body temperature was normal. Conclusion Sevoflurane for children induction can bring fewer stimuli in the respiratory tract, less cardiac vascular inhibition and palinesthesia time. Anaesthesia in children induced by sevoflurane is safe and effective.
出处
《中南大学学报（医学版）》
CAS
CSCD
北大核心
2007年第3期503-506,共4页
Journal of Central South University ：Medical Science
关键词
七氟烷
小儿
吸入麻醉
sevoflurane
children
inhalational anesthesia
