摘要
合成了标题席夫碱及其Ｃｕ（Ⅱ）、Ｚｎ（Ⅱ）、Ｎｉ（Ⅱ）配合物，对它们进行了元素分析、ＵＶ、ＩＲ，对配体进行了质谱和１ＨＮＭＲ等结构表征。还对化合物进行了抑制超氧阴离子自由基及消灭钉螺的生物活性研究。
2,4 dihydroxybenzaldehyde thiocarbohydrazone (C 15 H 12 N 2O 4S)and their complexes of copper(Ⅱ)、 zinc (Ⅱ) and nickel(Ⅱ) have been synthesized and characterized by elemental analysis, electronic absorption spectrum, IR, and molar conductivity. The Schiff base ligand has been further ascertained by 1HNMR and m.s. Spectra. The composition, coordination state and possible structures in these compounds are given. The tests of biological activity shows that complexes synthesized have scavenging effect on superoxide free radical similar SOD enzyme and these compounds are effective chemicals to kill oncomelania.
出处
《无机化学学报》
SCIE
CAS
CSCD
北大核心
1997年第1期68-72,共5页
Chinese Journal of Inorganic Chemistry
关键词
硫脲
金属配合物
席夫碱
生物活性
dihydroxybenzaldehyde thiourea copper(Ⅱ) zinc(Ⅱ) nickel(Ⅱ) oncomelania
