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普贝生用于足月妊娠引产对胎心、宫缩及羊水性状的影响 被引量：6

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摘要 [目的]探讨普贝生用于足月妊娠促进宫颈成熟时,对胎心、宫缩及羊水性状的影响,评估普贝生的安全性。[方法]采用随机对照研究,研究组40例使用普贝生阴道放置促进宫颈成熟,诱导产程发动;对照组60例采用美力斯(硫酸普拉酮)+催产素静滴诱导产程发动。统计各组用药后胎心异常的情况宫缩过频比例及临产后羊水性状。[结果]研究组宫缩过频在普贝生组明显增加(P<0.01),但晚期减速和变异减速的机率及羊水性状无显著性差异(P>0.05)。[结论]普贝生是一种安全、有效的促宫颈成熟药物,与美力斯(硫酸普拉酮)+催产素相比,不会增加不良反应的发生。
作者 余艳萍 何淑明
机构地区 中山市小榄人民医院产科
出处 《中山大学学报（医学科学版）》 CAS CSCD 北大核心 2007年第B06期182-183,共2页 Journal of Sun Yat-Sen University:Medical Sciences
关键词 普贝生 安全性 促宫颈成熟
分类号 R714 [医药卫生—妇产科学]
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参考文献4

二级参考文献17

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  • 2Lyrenas S, Clason I, Ulmsten U. In vivo controlled release of PGE2 from a vaginal insert during induction of labor. BJOG, 2001, 108(2) : 169
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共引文献369

同被引文献44

  • 1何平,张广兰,张建平.普贝生用于足月妊娠促宫颈成熟的探讨[J].中国妇幼保健,2004,19(3):32-33. 被引量：28
  • 2Kalkat RK, McMillan E, Cooper H, et al. Comparison of dinoprostone slow release pessary (Propess) with gel (Prostin) for induction of labour at term-a randomised trial[J]. J Obstet Gynaecol, 2008,28 (7) : 695.
  • 3Arduini M, Giri C, Giannone L, et al. "prepidil versus propess":pharmacological induction of labour with dinoprostone[J]. Minerva Ginecol, 2008,60(2) : 127.
  • 4E1-Shawarby SA, Connell RJ. Induction of labour at term with vaginal prostaglandins preparations: a randomised controlled trial of prostin vs propess[J]. J Obstet Gynaecol,2006,26(7) :627.
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  • 10Lyrenas S,Clason I,Ulmsten U.ln vivo controlled release of PGE2 from a vaginal insert(0.8mm. 10mg)during induction of labour[J].BJOG,2001,108(2): 169-178.

引证文献6

二级引证文献19

中山大学学报（医学科学版）
2007年 第B06期

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