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呼吸机相关性气管-支气管炎和肺炎的对比研究 被引量：3

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摘要 [目的]探讨老年机械通气患者呼吸机相关性气管支气管炎和肺炎的临床和病原学特点,为临床更好地防治呼吸机相关的院内感染提供帮助。[方法]分析92例机械通气>48 h老年患者的资料,依据临床症状、X线胸片和下呼吸道分泌物的细菌培养结果,将符合标准的研究对象分成38例呼吸机相关性肺炎(VAP)组和32例呼吸机相关性气管-支气管感染(VAT)组。分析两组发生率、病原学和预后差异。[结果]VAP、VAT发生率分别为41.3%和34.8%,13例VAT(40.6%)继发VAP。对比VAT组,VAP组机械通气2周前使用抗生素、COPD患者的比率显著增高,感染发生滞后,病死率高,机械通气时间、ICU时间延长,差异均有显著性(P<0.05)。VAP组前四位致病菌是铜绿假单胞菌、金黄色葡萄球菌、鲍曼不动杆菌、真菌。VAT组是铜绿假单胞菌、肺炎克雷伯菌、大肠埃希氏杆菌、鲍曼不动杆菌。分离的G-菌株70%为多重耐药菌株,亚胺培南耐药率最低。[结论]VAT的早期发现和控制,有利于防止VAP发生,并降低病死率。
作者 吴健 陈竹君
机构地区 广东省人民医院东病区呼吸科 广东省人民医院东病区重症监护室
出处 《中山大学学报（医学科学版）》 CAS CSCD 北大核心 2007年第B06期139-141,共3页 Journal of Sun Yat-Sen University:Medical Sciences
关键词 呼吸机相关性肺炎 呼吸机相关性气管-支气管炎 机械通气 院内感染 重症监护室
分类号 R563 [医药卫生—呼吸系统]
  • 相关文献

参考文献13

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二级参考文献11

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共引文献5

同被引文献20

引证文献3

二级引证文献8

中山大学学报（医学科学版）
2007年 第B06期

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