摘要
为评价部分喉切除术治疗声门癌的效果,总结1974~1994年期间治疗声门癌患者132例,随访至1994年12月,获得随访资料者126例(95%),进行统计分析。所有病例均经组织病理学证实为喉癌,根据TNM分期,T1、T298例(77.8%),T3、T428例(22.2%)。1例T4N1,其他均为N0。就诊时全部患者均为M0。126例患者均系采用部分喉切除治疗,其中89例为单纯手术治疗,术前放射治疗4例,术后放射治疗33例。应用Kaplan-Meier法进行生存率分析,结果126例中3年、5年和10年生存率分别为94.7%、89.1%和86.1%;T1、T2组3年、5年和10年生存率分别为:97.8%、95.1%和93.3%;T3、T4组为83.2%、62.7%和52.3%。患者术后均保存了喉的发音功能,能用语言进行社交,喉功能恢复良好。结论:部分喉切除术是治疗声门癌的最佳选择。
To evaluate the effect of partial laryngectomy for the treatment of glottic carcinoma, 126 patients with glottic carcinoma were reviewed. Between 1974 and 1994, 132 patients with glottic carcinoma were treated. Up to Dec. 1994, 126 cases (95%) had been followed up and analyzed statistically in this paper. According to TNM classification (UICC 1987), 98 (77.8%) of them were T 1,2 , 28 (22.2%), T 3,4 . One patient was T 4N 1 , and the rest 125 were No. All patients were M0 on admission. A total of 126 patients underwent partial laryngectomy. Among these patients, 89 were treated with surgical procedures alone, and 4 received pre operative 33 post operative, radiotherapy. Survival curves were plotted by the method of Kaplan and Meier. The results showed that three year, five year and ten year survival rates for 126 patients were 94.7%、89% and 86.1% respectively; Those for group of T 1,2 were 97.8%, 95.1% and 93.3%; For T 3,4 were 83.2%、62 7% and 52.3%. All patients preserved their voice and were able to communicate by speech after operation. The function of larynx was satisfactory. It was concluded that partial laryngectomy is preferable choice for the treatment of glottic carcinoma.
出处
《中华耳鼻咽喉科杂志》
CSCD
1997年第3期142-144,共3页
Chinese Journal of Otorhinolaryngology
关键词
喉肿瘤
喉切除术
存活率
声门癌
Laryngeal neoplasms Laryngectomy Survival rate