摘要
为探讨恶性造釉细胞瘤和造釉细胞癌的临床病理特点,及两个名称的自然历史和意义,我们对24例恶性造釉细胞瘤(造釉细胞癌)的临床病理资料进行了研究,并对两个名称各自的实质进行了探讨。结果:其组织病理特点为滤泡周边细胞增生,可呈乳头状突向间质,核增大中度异型,核深染或呈空泡状,核分裂相增加,星网状细胞消失被肉瘤样细胞取代。其中19例5~30年随访结果为:11例生存;3例1次复发,3例2次复发(其中1例复发后死亡),1例4次复发后死亡,1例13年无复发死于它病。结果提示:“恶性造釉细胞瘤”这一名称更为科学。
Twenty four cases of malignant ameloblastoma were reported, among them were nineteen cases followed up for 5 to 30 years. Histologic characteristics include predominated proliferation of the peripheral cells with papillary protruding to stroma, replacement of the stellate reticular cells in the follicular center by sarcomatous cells, as well as large and deep stained or alveolar nuclei with moderate atypia, and high mitosis of the tumor cells. Clinico radiologically, the tumor showed malignant features such as fast growing recently, pain, anesthesia, cauliflower ulcer, limited mouth opening, and large multilocular radiolucent area with ill defined border. The biological behavior, nomenclature of the ameloblastic carcinoma or malignant ameloblastoma, and differential diagnosis from other tumors were also discussed.
出处
《中华口腔医学杂志》
CAS
CSCD
北大核心
1997年第3期169-171,共3页
Chinese Journal of Stomatology
关键词
颌面部肿瘤
造釉细胞瘤
病理学
Pathology
oral
Ameloblastic carcinoma
Malignant ameloblastoma