摘要
结缔组织生长因子(connective tissue growth factor,CTGF)是即刻早期基因CCN家族的成员之一。CTGF与细胞外基质相互作用,可调节细胞间的粘附迁移、促进有丝分裂的发生、细胞活化和参与血管的生成。CTGF的表达水平与多种组织恶性肿瘤的发生进展、浸润转移、血管生成及其预后密切关联。
The connective tissue growth factor（CTGF） is a member of an emergine gene family known as the CCN family. CTGF works with extracellular matrix and can promote cell migration, adhesion, mitochysis, survival and angiogenesis. The expression of CTGF may be an important biological marker reflecting the carcinogenesis and progression, infiltration and invasion, angiogenesis and progno- sis of tumors.
出处
《川北医学院学报》
CAS
2007年第6期609-612,共4页
Journal of North Sichuan Medical College
