摘要
晕痣以色素痣绕以圆形或椭圆形局限性色素减退为特征,中心痣大多是后天性痣细胞痣。CD8+为主的T细胞清除痣细胞是发病机制中的关键环节。晕痣与白癜风、黑素瘤在抗原及免疫反应模式方面密切相关。尽管目前认为,对晕痣患者进行随访是最好的治疗策略,但手术切除有助于平息晕痣的免疫活动,因此对于单发皮损,手术切除也许更为合适。
Halo nevus（HN） is characterized by a pigmented nevus surrounding by round or oval local depigmentation. The central nevus is usually an acquired nevocyte nevus. It plays a key role in the pathogenesis of HN that cytotoxic CD8＋ T cells eliminate central nevus. HN is closely correlated with vitiligo and melanoma in antigens and immune response pattern. Though clinical follow-up is commonly considered as the optimal treatment for HN presently, surgical resection could help to subside immunological activity in HN, so surgical resection may be more appropriate for single lesion of HN.
出处
《国际皮肤性病学杂志》
2007年第6期355-357,共3页
International Journal of Dermatology and Venereology
关键词
痣色素
白癜风
黑素瘤
Nevus pigmented
Vitiligo
Melanoma
