摘要
对１５３例恶性血液病（ＨＭ）医院感染（ＮＩ）回顾性调查表明ＨＭ的医院感染率（ＮＩＲ）５２．９％。ＮＩＲ粒细胞缺乏组（粒缺组）８７．２％，非粒细胞缺乏组（非粒缺组）４１．２％（Ｐ＜０．００５）；因ＮＩ死亡人数粒缺组６例，非粒缺组１例（Ｐ＜０．００５）；ＮＩ患者人均感染粒缺组１９．２ｄ，比非粒缺组多１０ｄ（Ｐ＜０．００１）。急性白血病（ＡＬ）与淋巴瘤的ＮＩＲ经ｘ２检验Ｐ＞０．０５，ＨＭ患者肝炎病毒携带与否其ＮＩＲ差异无统计学检验显著意义。粒细胞缺乏是ＨＭ患者发生ＮＩ主要危险因素，提高功能完善的粒细胞数是防治ＨＭ的ＮＩ关键之一。
An investigation was made on 153 hospitalized patients with hematologic malignancies (HM). The main results showed the nosocomial infection rate (NIR) was 52.9%.The NIR of these patients with agranulocytosis was 87.2% while that of those with non agranulocytosis 41.2% (P<0.005), and average duration of nosocomial infection of the former was 19.2 days while that of the latter was 8.8 days (P<0.001)。 There was no difference statistically between NIR of acute leukemias group and that of lymphoma one .The NIR of HM seemed not to be consistenat with whether hepatitis viruses were carried by the patients. Agranulocytosis was the main risk factor of NIR of patients with HM.
出处
《中华医院感染学杂志》
CAS
CSCD
1997年第2期79-81,共3页
Chinese Journal of Nosocomiology
关键词
血液病
癌
医院感染
Hematologic malignancy Nosocomial infection Agranulocytosis Hepatitis virus
