摘要
通过对犬冠状病毒TN449株纤突蛋白基因的克隆测序,将获得的序列与GneBank中登陆的犬冠状病毒不同毒株S基因序列进行比较,分析它们的同源性、差异程度,同时绘制核苷酸序列及其氨基酸序列的系统进化树。有助于了解犬冠状病毒的抗原变异、血清型和毒力变化规律。
The paper expounds the cloning and sequencing of the spike protein gene of Canine coronavims TN449 strain. The sequence is compared to the S genes of different Canine comnavims strains announced at GeneBank so to analyze their homology and diversity dezree,Besides, the article drafts the Phylogenetic tree of their nucleotide and amino acid. Those studies will be of ase in undestanding the antigen variation, serotypes and the changing rules of virulence of Canine eoronavirus.
出处
《黄山学院学报》
2007年第5期71-74,共4页
Journal of Huangshan University
关键词
犬冠状病毒
纤突蛋白
序列分析
canine coronavirus
spike protein
sequerce analysis.
