摘要
目的观察中药胃肠通对胃肠功能紊乱的治疗作用．方法胃肠功能紊乱患者６４例用胃肠通（由白芍、甘草、大黄等组成）１０ｍｌ～２０ｍｌ，３／ｄ，餐前服，２周．动物试验观察胃肠通对健康成年Ｗｉｓｔａｒ大鼠胃排空及小肠内容推进的影响．结果胃肠通对呕吐、食欲不振、便秘、排便不畅等症状卓有成效，有效率９０％以上．动物实验证实胃肠通能使胃排空开始时间从１００３ｍｉｎ±６２ｍｉｎ缩短至７８５ｍｉｎ±４５ｍｉｎ；小肠内容推进速度从１２４ｃｍ／ｍｉｎ±０１４ｃｍ／ｍｉｎ加快至２２８ｃｍ／ｍｉｎ±０４５ｃｍ／ｍｉｎ．结论中药胃肠通是经济有效的促胃肠动力药．
AIM To investigate the effect of Weichangtong (WCT) (consisting of Paeonia Albiflora Pall, Glycyrrhiza and Rhubarb) on disorders of gastrointestinal motility. METHODS Patients with gastrointestinal motility disorders ( n =64) were given WCT 10ml～20ml, po, tid, and its effect on gastric emptying and velocity of intestinal transit was observed in rats. RESULTS WCT was effective for gastrointestinal motility disorders, especially for vomiting, loss of appetite, constipation and poor bowel movement, the effective rate being above 90%. The time of gastric emptying (100 3min±6 2min to 78 5min±4 5min) and velocity of intestinal transit (1 24cm/min±0 14cm/min to 2 28cm/min±0 45cm/min) were significantly accelerated ( P <0 01) after WCT treatment in rats. CONCLUSION WCT is an effective gastrointestinal prokinetic drug.
关键词
胃肠功能紊乱
胃肠通
中医药疗法
中药品
Dyspepsia/TCM therapy\ \ Colonic diseases, functional/TCM therapy
