摘要
目的研究睡眠呼吸暂停综合征（ＳＡＳ）与夜间心绞痛的关系。方法对伴有或不伴有ＳＡＳ的老年冠心病患者９２例进行睡眠呼吸暂停和动态心电监测以及夜间心绞痛、无症状心肌缺血的观察。结果ＳＡＳ组夜间心绞痛１６例（３４８％），心肌缺血２７例（５８７％），心律失常４１例（８９１％），均较无ＳＡＳ组的４例（８７％）、８例（１７４％）和１６例（３４８％）明显增加（均为Ｐ＜００１）。夜间心绞痛和无症状心肌缺血发作次数与呼吸暂停次数、持续时间呈显著正相关（ｒ＝０４７５～０６１３，Ｐ＜００１），与血氧饱和度呈显著负相关（ｒ＝－０５２６，Ｐ＜００１）。ＳＡＳ患者经治疗夜间心绞痛和无症状心肌缺血显著改善（Ｐ＜００１）。结论老年人ＳＡＳ与夜间心绞痛有关。
Objective\ To investigate the relationship between nocturnal angina and sleep apnea syndrome (SAS). Methods\ The patients were observed for slppe apna, angina pectoris and dynamic electrocardiogram, including 54 cases of coronary disease in the aged with and without SAS.\ \ Results\ The results showed that there were nocturnal angina in 16 cases (34.8%), myocardial ischemia in 27 case (58.7%) and arrhythmia in 41 cases (89.1%) which were significantly more in SAS group than in the control group (P<0.01). Nocturnal angina and asymptomatic myocardial ischemia were positively correlated with the frequency and duration of apnea ( r =0.457-0.613, P <0.01) and negatively correlated with SaO 2 ( r =-0.526,P<0.01). After treatment the nocturnal angina and asymptomatic myocardial ischemia were markedly improved in SAS patients.\ \ Conclusions These facts suggest that nocturnal angina pectoris is related to SAS in the aged.
出处
《中华老年医学杂志》
CAS
CSCD
北大核心
1997年第3期156-158,共3页
Chinese Journal of Geriatrics
基金
解放军南京军区重点科研基金
关键词
睡眠呼吸暂停
综合征
并发症
心绞痛
老年人
sleep apnea syndrome\ \ coronary disease\ angina pectoris\ arrhythmia
