摘要
目的探讨老年人食管酸暴露频率强度与胃食管反流病的关系。方法应用食管ｐＨ测定方法，对４１例有胃食管反流症状者和１５例健康老年人进行２４小时食管ｐＨ监测。结果健康老年人ｐＨ＜４的总时间百分比＜３３％，立位ｐＨ＜４时间百分比＜５５％，反流＞５分钟次数＜２次，ｐＨ＜４反流次数＜６５次，但卧位ｐＨ＜４时间百分比为＜１４％。４１例有胃食管反流症状者中，３８例酸反流得分＞１４５，包括１５例内镜下无食管炎征象者，阳性率达９２５％。根据内镜下有无食管炎，比较食管粘膜损伤组与无食管粘膜损伤组之间各项ｐＨ指标的异同。可见ｐＨ＜４的总时间百分比、卧位ｐＨ＜４时间百分比和持续反流＞５分钟次数有明显不同。结论老年人食管粘膜暴露频率时间与胃食管反流病的严重程度有关。
Objective To study the relationship between frequency of esophageal acid exposure and gastroesophageal reflux disease(GERD). Methods Esophageal pH was measured in15healt hyaged subjects and 41 cases with GERD by 24 hour esophageal pH monitoring. Results Norm alvalues from 15 healthy aged subjects were obtained.Percent of total time pH<4and percent of uprig httime pH<4were less than3 3%,5 5%respectively.The number of reflux episodes and episod eslonger than5min were less than65and2times respectively.But percent of supine time pH<4was les sthan1 4%.Compared with healthy subjects,composite score in38patients was larger than14 5,thepositive rate of GER was92 5%.We also compared pH parameter between patients with esophagit isand without esophagitis,which were diagnosed by endoscopy.Percent total timepH<4,percent supin etime pH<4and the duration of the longest reflux episode had significant difference between the two groups. Conclusions It was suggested that duration of esophageal acid exposure is associat ed with the severity of GERD.Twenty four hour pH monitoring is asensitive method for patients with GERD who have no endoscopic evidence of esophagitis.
出处
《中华老年医学杂志》
CAS
CSCD
北大核心
1997年第3期141-143,共3页
Chinese Journal of Geriatrics
关键词
胃食管返流
诊断
食管炎
消化性
诊断
gastroesophageal reflux esophagitis,peptic endoscopy,digestive system
