抑癌基因P16和突变型P53蛋白产物在膀胱癌中表达的意义
被引量:1
摘要
抑癌基因P16和突变型P53蛋白产物在膀胱癌中表达的意义平季根郭震华陈赐龄王晖我们应用免疫组化ABC法和微波抗原修复法对膀胱癌组织标本中抑癌基因P16和突变型P53蛋白产物进行检测,探讨其表达特征和临床意义。材料与方法1989~1991年间手术的原发...
出处
《中华泌尿外科杂志》
CAS
CSCD
北大核心
1997年第6期355-355,共1页
Chinese Journal of Urology
同被引文献22
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1袁建林,王剑波,于茂生,李青,辛建国,郭炜.抑癌基因P16在膀胱肿瘤中的表达及意义[J].中华泌尿外科杂志,1995,16(12):722-724. 被引量:19
-
2Kamb A, Gruis NA. Weaver-Feldhaus J,et sl. A cell cycle regulator ,potentially involved in genesis of many tumor types. Science, 1994, 264:436.
-
3Moborl T,Miura K, Wu DJ, et al. Deletions of the cyclin dependent kinase-4 inhibitor gene in multiple human cancer. Nature (Lond), 1994,366:753.
-
4Liu Q, Neuhausen S, Mcclure M, et al. CDKN2 (MTS1) tumor suppressor gene mutations in human tumor cell lines. Oncogene, 1995,10:1061.
-
5Xu-HJ,Cairus P,Hu SX ,et al, Loss of Rb protein expressioa in primary bladder cancer correlates with loss of heterozygosity at the Rb, Locus and tumor progression, Int J Cancer, 1993;53:781.
-
6Spruck CHI. Gonzaleaz-Zulueta M, Shibata A, et al. P16 gene in uncultured tumors. Science, (Washington Dc), 1994;64:183.
-
7Walker DG Dan W. popovic EA, et al. Homozygous delection of the multinle tumor suppressor gene I in the progression of human astcocyromas. Cancer Res, 1995,55: 20.
-
8Caldas C,Hahn SA,Dacosta LT,et al. Fxenquent amostic.mutations and homozygous deletios of tha p16;(MTS1)gene in pancreatic adenocarcinoma. Nature Gent, 1994,8:27.
-
9Serrano M, OJ,Beach D, Anew regulatory motic in cellcycle control causing specific inhibition of cyclin/CDK4.Nature (Lond), 1993,366:704.
-
10Reed JA, Loganzo F, Shca CR, et al. Loss of expression of the p16/cylin-dependent kinase inhibitor 2 tumor suppressor gene in metanocytic Lessions correlates with invasive stage of tumor progression. Cancer Res. 1995,55:2713.
-
1翟秀云.鼻咽癌组织VEGF、TNF-α及其受体VEGFR1、P55的表达及意义[J].医学与哲学(B),2009,30(10):59-61.
-
2王立新,洪永青,王继鹏.非小细胞肺癌组织中VEGF、p16及p53蛋白的表达及意义[J].山东医药,2009,49(43):58-59.
-
3Rzymski P.,Opala T.,Wilczak M.,杨晓梅.血清肿瘤坏死因子α受体p55/p75比值与卵巢癌检测[J].世界核心医学期刊文摘(妇产科学分册),2005,0(7):52-52.
-
4傅寅佳,杨熹,曹小年,来森艳,王桂华,胡俊波,李襄.p53通过调控p55PIK抑制肝细胞癌SMMC-7721细胞的增殖[J].华中科技大学学报(医学版),2015,44(3):247-250. 被引量:3
-
5高涵,孙晓杰,周涛,师岩,张梅,李珅,李淑艳.腺病毒介导p55γ基因N末端的过表达对胃癌细胞增殖的影响[J].中国医药导报,2009,6(35):17-19. 被引量:1
-
6孙晓杰,赵玫,袁兴华,王晓霞,马萍,孙跃民,黄常志.PI3K p55γ调节亚单位N末端24个氨基酸抑制胃癌细胞增殖[J].肿瘤,2005,25(1):24-27. 被引量:3
-
7姚继红,A·AWani,等.破坏泛素依赖的蛋白水解通路对p55转录活性的抑制作用[J].中国药理学会通讯,2002,19(2):10-12.
-
8冯丽,孙晓杰,高涵,李珅,张梅.腺病毒介导p55γ基因N末端的过表达对胃癌细胞增殖和迁移的抑制[J].癌变·畸变·突变,2009,21(6):409-412. 被引量:1
-
9高蕾,白岚,石卫民,南清振,毛战斌.X线照射对大肠癌细胞株Lovo细胞TNFR-p55表达及释放的影响[J].南方医科大学学报,2007,27(12):1921-1923.
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10许远,郑志强,王飞海,俞耀军.结肠癌组织TNF-α及p55与肿瘤细胞分化程度的相关性研究[J].中国肛肠病杂志,2010(1):9-11.