摘要
报道了无溶剂法合成N-(2-羟乙基)-邻苯二甲酰亚胺。邻苯二甲酸酐与乙醇胺在无溶剂的条件下反应,质量收率达到99%以上,质量分数99%以上。讨论了反应温度,反应时间,物料比例及不同后处理方式对反应质量收率和质量分数的影响。该方法操作简便,实验条件温和,后处理简便,设备投入少,无污染,适合工业化生产。
The solvent-free synthesis of N-（2-hydroxyethyl）phthalimide was reported. The reaction of phthalic anhydride and aminoethyl alcohol under solvent-free conditions provided a novel route to N-（2- hydroxyethyl）phthalimide with good yields（〉99%） and high purity（〉99%）. The influence of reaction temperature, reaction time, ratio of the reactant and different post treatment on the yield and high purity were discussed. This method is endowed with several unique merits, namely, simple procedure, convenient aftertreatment, mild and environmentally friendly conditions, and may be practical for commercial orocess.
出处
《浙江化工》
CAS
2007年第10期4-5,共2页
Zhejiang Chemical Industry
