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急性有机磷中毒阿托品合理治疗剂量观察指标的护理研究 被引量:20

Study on observation Indexes of Rational Dosage of Atropine in Treatment of Acute Organophosphorus Insecticides Poisoning
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摘要 为探讨急性有机磷农药中毒阿托品合理治疗剂量的护理观察指标,应用我院前期研究中得出的急性有机磷中毒阿托品合理治疗剂量以能始抗蓄积的乙酰胆碱,又不引起机体太大反馈调节为宜的理论,总结出异常分泌物、体温和脉搏王项护理观察指标,以这三项指标的变化来指导阿托品用量,观察治疗了171例急性有机磷中毒患者(A组),并与按传统观察方法(阿托品化指征)治疗的184例(B组)进行比较,结果A组比B组显著减少了阿托品用量(P<0.001),缩短了治疗时间(P<0.001),降低了并发症和病死率(P均<0.05)。表明该观察指标是科学可靠的,具有实用和推广价值。 In order to obtain nursing observation indexes in treatment of acute oopnophosphorus insecticidesPoisoning (AOIP) with rational atropine dosage, three nursing obsetvation indexes: abnormal secretion, bodytemperature and pulse were summarized with the theory obtaified from a earier study in our hospital. Theratboal atroPine dosage for treatment of AOIP should be enough to antagonize the accumulation ofacetylcholine but should not cause too much body feedback regulation. Regulate atropine dose by changes ofthese three indexes, 171 patients with AOIP (Group A) were treated and observed, and compared with 184patients (Group B) treated with traditional observating method (atropinization index). The results showed thatthe atropine dose used in Group A was marked1y less than that in Grop B (P < 0. 001 ), the medicationduration was shortened (P <0.001), the complication and fatality rate were decreased (both P < 0. 05 ). Itindicated that these observation indexes are scientific and reliable, practical and of spreading value.
出处 《中华护理杂志》 CSCD 北大核心 1997年第6期311-315,共5页 Chinese Journal of Nursing
关键词 有机磷农药 农药中毒 阿托品 药物疗法 护理 Insecticides,Organophosphorus,Atropine, Nursing
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二级参考文献6

  • 1叶传勇,中华内科杂志,1992年,31卷,534页
  • 2潘思源,中国药理学报,1991年,12卷,344页
  • 3叶传勇,中华内科杂志,1992年,9卷,533页
  • 4张文武,中国急救医学,1991年,11卷,29页
  • 5潘思源,中国药理学报,1991年,2卷,148页
  • 6王世俊,中华内科杂志,1991年,2卷,68页

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