摘要
目的:观察中老年2型糖尿病患者的认知特点及相关影响因素。方法:对155例2型糖尿病患者进行问卷调查,了解糖尿病患者认知状态以及记忆和非记忆功能的相关影响因素。结果:2型糖尿病患者的认知功能不仅与患者的年龄(r=-0.366)、性别(r=-0.374)、文化程度(r=0.574)、家庭收入(r=0.268)相关,而且与糖尿病病程(r=-0.247)、血糖(r=-0.269)、HbA1C(r=-0.235)以及收缩压(r=-0.280)等因素有关。合并高血压与无高血压两组相比,在简易智能状态量表(MMSE)中的计算(P=0.006)、语言复述(P=0.006)及指图正确数(P=0.001)和指图总耗时(P=0.016)等方面均有差异。结论:2型糖尿病患者的认知功能减退与患者的年龄、性别、文化程度、家庭收入以及血糖控制情况、是否合并高血压及血压水平等因素有关。积极有效控制血糖、血压有利于减轻糖尿病患者的认知功能损害。
Objective：To study the cognitive function of middle-age and old patients with type 2 diabetes mellitus（T2DM） and related factors. Methods：Questionnaires were used to investigate 155 patients with T2DM to study the cognitive function and the possible infected factors of memory and non-memory. Results：Cognitive function of the patients with T2DM was not only associated with age（r = -0.366）,sex（r = -0.374）,educational level（r = 0.574） and incomes（r = 0.268）,but also with course of diabetes disease（r = -0.247）,the levels of blood glucose（r = -0.269）,HBA1C（r = -0.235） and systolic pressure（r = -0.280）. The patients with T2DM combined hypertension displayed significant difference to the controls in calculating（P = 0.006） and repeating sentence（P = 0.006） in MMSE,the right numbers of point pictures（P = 0.001） and the expended time of point pictures（P = 0.016）. Conclusion：The impairment of cognitive function of middle-age and old patients with T2DM was concerned with age,sex,educational level,incomes,and the levels of blood glucose,combined hypertension and the level of hypertension. Control the level of blood glucose and hypertension effectively should prevent and mitigate the deterioration of cognition of T2DM.
出处
《南京医科大学学报（自然科学版）》
CAS
CSCD
北大核心
2007年第9期1000-1004,共5页
Journal of Nanjing Medical University(Natural Sciences)
关键词
认知障碍
2型糖尿病
cognition disorders
type 2 diabetes mellitus
