摘要
新西兰大白兔随机分为三组 ,即正常对照组 ( n=6) ;肝硬变肠外营养 ( PN) - L CT组 ( n=10 ) ;肝硬变肠外营养 - MCT/L CT组 ( n=11)。两组的 PN液所含热量及氮量均相等。在 PN的第1、7天 ,用高效液相色谱 ( HPL C)测定 PN后 4 h血中游离脂肪酸 ( FFA)浓度 ,并常规测定胆红素及白蛋白和肝脏酶学的变化。结果表明肝硬变形成后 ,总胆红素及直应胆红素、丙氨酸转氨酶( AL T)、天门冬氨酸转氨酶、碱性磷酸酶、γ-谷酰转肽酶均明显升高 ,而白蛋白明显下降 ,P<0 .0 1。PN期间 ,FFA及 FFA/白蛋白 ( Alb)摩尔比值也明显升高 ,P<0 .0 1。PN第 7天时 ,LCT组直应胆红素及 AL T和 FFA/白蛋白 ( Alb)摩尔比值均明显高于 MCT组 ,P<0 .0 1;结果提示 。
The rabbits with cirrhosis were in- duced by ligating common bile duct,and the animals were divided into three groups randomly,namely,nomal,LCT- PN and MCT/ LCT group.Serm free fatty acid (FFA) was measured by HPL C,and biliru- bin,albumin and liver enzymes were mea- sured.The results showed that TBil,DBil, ALT,AST,AKP,γ- GT markedly in- creaseed in cirrhotic rabbit,and ablumin markedly decreased(P<0 .0 1 ) .After PN7 day,ALT,FFA and FFA/ Alb in group L CT were higher than in group MCT/ L CT.This study indicated thatintravenous lipid emulsion containing MCT was an ide- al nutritional souce for the cirrhotic pa- tients.
出处
《肠外与肠内营养》
CAS
1997年第3期149-152,共4页
Parenteral & Enteral Nutrition
关键词
中链脂肪乳剂
长链脂肪乳剂
肝硬变
胆红素
Medium- chain- triglyc- eride Long- chain- triglyceride L iver cirrhosis Bilirubi
