摘要
目的:评价传统针剌治疗香港地区慢性疲劳综台征(chronic fatigue syndrome,CFS)的临床疗效。方法:采用单盲、随机、对照研究方法,将99例合恪受试者按1:1比例随机分成治疗组50例和对照组49例。治疗组以传统针刺法,选取百会、足三里、三阴交穴治疗;对照组以平针按穴法(针不刺入皮肤),选穴同治疗组。疗程共4周。每周治疗2次。按照英国Trudie Chalder等制定的疲劳量表和美国疾病控制中心1994年制定的CFS诊断标准及SF-12生活质量量表,建立效应评价表,评价疗效及安全性。结果:治疗后两组临床症状得到改善,在身体疲劳、精神疲劳及SF-12生活质量方面,治疗组优于对照组(P<0.01或P<0.05);受试者未发现不良反应。结论:针剌治疗CFS安全有效。
Objective： To evaluate the efficacy of acupuncture in treating chronic fatigue syndrome （CFS） in Hong Kong. Methods： A single-blinded, randomized controlled trial design was adopted. Participants meeting inclusion criteria were randomly assigned to a treatment and a control group according to 1 ： 1 ratio, resulting in an effective sample size of 99, with 50 and 49 patients in treatment and control group respectively. The same set of acupuncture points, which were selected according to traditional Chinese medicine theories, was applied in both groups, while conventional needle acupuncture was applied in treatment group and sham acupuncture （without skin penetration） was applied in control group. Schedule of treatment was the same in both groups, i.e. twice a week for 4 weeks. Key outcome measures were Chalder＇s Fatigue Scale, diagnostic criteria for CFS of the US＇s Centre for Disease Control and SF-12 health-related quality of life （HQOL） questionnaire. Adverse events, if any, were recorded. Results： Improvements in physical and mental fatigue and HQOL in both groups were observed, but the improvements in treatment group were significantly bigger than in control group （P〈0.01 or P〈0.05）. No adverse events occurred. Conclusion： Acupuncture is a safe, effective treatment for CFS.
出处
《中西医结合学报》
CAS
2007年第6期630-633,共4页
Journal of Chinese Integrative Medicine
基金
香港大学基础研究种子基金(No.10206110.35405.22100.302)
关键词
慢性疲劳综合征
针刺
临床试验
chronic fatigue syndrome
acupuncture
clinical trials
