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脑氧饱和度预测心脏术后情感性精神障碍的研究 被引量:10

Predicting affective disorder with rSO_2 in patients underwent cardiac surgery
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摘要 目的研究脑氧饱和度(rSO2)监测在评估心脏手术后情感性精神障碍方面的价值。方法择期行心脏手术患者62例,其中心肺转流(CPB)下心脏手术患者40例,非CPB下冠状动脉搭桥术患者22例。术中监测rSO2,术前和术后第7天采用Zung氏焦虑自评量表(SAS)及抑郁自评量表(SDS)对患者进行情感障碍评价。比较rSO2降低的最低数值及降低的曲线下面积两种标准在评估术后情感障碍方面的不同功效。结果CPB患者中有9例出现术后轻度情感障碍。其中术中rSO2低于40%者有5例,低于50%的曲线下面积大于600的8例。经统计分析后表明通过CPB期间rSO2低于50%的曲线下面积作为评估发生术后情感障碍的差异有统计学意义。结论rSO2监测可作为心脏手术中大脑氧供需平衡监测的可靠方法。将rSO2低于50%的曲线下面积作为评估术后情感障碍的标准更具有临床意义。 Objective To evaluate the relationship between cerebral oxygen saturation (rSO2) and the affective disorder after cardiac surgery. Methods Sixty-two patients underwent elective cardiac surgery were enrolled in this study, of which forty were with cardiopulmonary bypass(CPB), and the others were OPCAB. rSO2 was monitored during operation. Affective disorder was assessed by the Self-rating Anxiety Scale (SAS) and Self-rating Depression Scale (SDS) one day before and on the 7th day after surgery. Two methods of grouping, with the nadir rSO2 under value and the area of rSO2 under the curve were used to evaluate the differences between the two groups. Results Nine patients with affective disorder presented after cardiac surgeries with CPB, of which five with the nadir rSO2 under 40% and the eight with the areas of rSO2〈50% more than 600. Analysis showed that compared with the nadir rSO2 under 40%, taking the criterion of the areas of rSO2 〈50% more than 600 got more significant results. Conclusion The rSO2 monitoring is useful for assessment of cerebral oxygenation during cardiac surgery. The areas of rSO2 〈 50% can be a predictor for postoperative affective disorder.
出处 《临床麻醉学杂志》 CAS CSCD 2007年第10期812-814,共3页 Journal of Clinical Anesthesiology
关键词 脑氧饱和度 情感性精神障碍 心脏手术 Cerebral oxygen saturation Affective disorder Cardiac surgery
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参考文献5

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二级参考文献29

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