摘要
目的分析原发病灶局限于黏膜或黏膜下层,但同时伴有远隔转移早期胃癌的临床病理特征。方法回顾性分析1973年4月至1998年11月,中日两家大学8所附属医院的4420例（每家医院220～1270例）早期胃癌,其中22例伴有远隔转移。分析伴远隔转移的早期胃癌（远转组）和不伴远隔转移的早期胃癌（无转组）在性别、年龄、肿瘤大小、浸润深度、分化类型、长期存活率等方面的差异。结果远转组肿瘤与无转组在性别、肿瘤大小、浸润深度、5年存活率（远转组34.7%,无转组91.3%）方面差异有非常显著性意义（P〈0.01）;两组在年龄、分化程度方面差异无显著性意义。结论早期胃癌也可能发生远隔转移并导致预后不佳。女性、肿瘤浸润至黏膜下层且肿瘤直径〉4cm可能是早期胃癌发生远隔转移的危险因素。
Objective To analyze clinical pathological characters of early gastric cancer with distant metastasis. Methods The clinical data of 4 420 patients with early gastric cancer admitted between April 1973 and November 1998 in 8 hospitals of Chinese and Japanese university were analyzed retrospectively. Among them, 22 patients had distant metastasis. The sex ratio, average age, maximum tumor diameter, infiltrating depth, differentiation type, and long term survival were compared between the distant metastasis （DM） group and non-distant metastasis （control） group. Results There were very significant differences of sex ratio, maximum tumor diameter, infiltrating depth, and 5 year survival rate （DM group 34. 7% ,control group 91.3% ） between DM group and control group （ P 〈0. 01 ）. There were no significant differences of age and differentiation type between the two groups. Conclusion Even early gastric cancer can have distant metastasis and poor prognosis. Female,tumor infiltrating submucosa and maximum diameter 〉4cm can be risk factors of early gastric cancer with distant metastasis.
出处
《中国实用外科杂志》
CSCD
北大核心
2007年第11期873-875,共3页
Chinese Journal of Practical Surgery
关键词
早期胃癌
远隔转移
early gastric cancer
distant metastasis
