摘要
本试验用自由基清除剂超氧化物歧化酶（ＳＯＤ）和还原型谷胱甘肽分别处理实验性传染性法氏囊病（ＩＢＤ）患鸡，以探讨自由基清除剂对ＩＢＤ发病过程的影响。结果表明ＳＯＤ和还原型谷胱甘肽处理过的ＩＢＤ患鸡，其临床症状、病理变化和凝血功能障碍均比攻毒对照组明显减轻，死亡率显著降低。说明自由基清除剂可在相当程度上阻断ＩＢＤ的发病过程。
Chickens inoculated with infectious bursal disease virus were treated with superoxide dismutase (SOD) and reduced glutathione to study the effects of free radical scavengres on pathologic process in infectious bursal disease (IBD).The results showed that there were the less severe clinical signs,pathologic changes and coagulation deficiency and the lower mortality in inoculated chicken treated with SOD and reduced glutathione than those in inoculated chickens with no treatment.This study indicated that free radical scavengers could considerably block the pathologic process in IBD,and therefore free radical plays an important role in the pathogenesis of IBD.
出处
《畜牧兽医学报》
CAS
CSCD
北大核心
1997年第4期362-365,共4页
ACTA VETERINARIA ET ZOOTECHNICA SINICA
关键词
传染性法氏囊病
发病
自由基清除剂
鸡病
Infectious bursal disease,Free radical,Free radical scavenger
