摘要
目的探讨肝硬化食管胃底静脉曲张患者非创伤性临床指标与出血的相关性。方法回顾性分析1992-2006年期间290例肝硬化住院患者的临床资料。先以单因素非条件Logistic回归分析筛选出有统计学意义的危险因素，再应用多因素非条件Logistic回归分析肝硬化食管胃底静脉曲张出血无创性独立危险因素。结果单因素分析表明：肝硬化病程、病前感染、食管静脉曲张程度、R-C征、脾厚、脾静脉宽度、门静脉宽度、门静脉血流速度、血小板、Bun、胆固醇、凝血酶原时间与出血相关。多因素分析表明脾厚、门静脉宽度、腹水征、血小板、白蛋白、凝血酶原时间是食管静脉曲张破裂出血无创性独立危险因素。结论肝硬化并发上消化道出血的无创性危险因素是脾厚、门静脉宽度、腹水征、血小板、白蛋白、凝血酶原时间。
Objective To evaluate the correlation between non-hurt clinical indexes and variceal bleeding in patients with cirrhosis. Method Retrospect the clinical material of the 290 cirrhotic inpatients during 1992--2006. fist, these materials were analysised by simple factor logistic regression analysis and choose the significative factor, second, these materials were analysised by multi-factor logistic regression analysis and choose the non-hurt risk factor for esophageal variceal hemorrhage in patients with liver cirrhosis. Results Results of simple logistic regression showed that there is a positive correlation between hemorrhage and course of diseases.in-fections.esophagus varix level.R-C sign.spleen thick.spleen vein diameter.postal vein diameter.portal vein blood velocity.Platelet count.Bun.cholesterol.prothrombin time. Logistic regression with multivariate analysis revealed that non-hurt independent risk factors of esophageal variceal hemorrhage in liver cirrhosis is spleen thick, postal vein diameter, ascites. Platelet count, albumin, prothrombin time. Conclusion The non-hurt independent risk factor of cirrhosis with esophageal varices hemorrhage is spleen thick.postal vein diameter.ascites.Platelet count.albumin.prothrombin time.
出处
《肝胆外科杂志》
2007年第5期357-359,共3页
Journal of Hepatobiliary Surgery
关键词
食管静脉曲张出血
无创性
危险因素
esophageal varices hemorrhage
non - hurt
risk factors
