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B细胞发育与功能行使的转录调控及其表观遗传学调节 被引量：1

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摘要 B细胞发育的研究取得了很大进展。B细胞产生及分化发育的主线已被确定。E2A-EBF-Pax5转录调节网络对B细胞形成至关重要。众多的转录因子在后续的B细胞分化发育以及B细胞应答中发挥关键作用。与转录调节一样,表观遗传学调节已开始被证实对B细胞发育及功能十分重要,将是B细胞生物学快速发展的领域。
作者 孙健
机构地区 上海市免疫学研究所中科院上海生命科学研究院/上海交通大学医学院健康科学研究所
出处 《现代免疫学》 CAS CSCD 北大核心 2007年第5期353-358,共6页 Current Immunology
关键词 B细胞发育 B细胞应答 转录因子 表观遗传学调节
分类号 R392.12 [医药卫生—免疫学]
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参考文献22

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同被引文献25

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现代免疫学
2007年 第5期

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