摘要
目的：研究１０年间垂体泌乳素（ＰＲＬ）腺瘤临床特征变化的特点。方法：采用回顾性研究手段，对１０年间的１１４例垂体ＰＲＬ腺瘤的临床内分泌症状、激素分泌特征、影像学检查变化的特点进行了对比观察。结果：近年来垂体ＰＲＬ腺瘤在垂体腺瘤中的比例已逐渐升高（达４４％），以内分泌症状为主诉者逐渐增加，但仍有许多患者的内分泌症状在视觉症状出现前被忽视了。本组６０．２％的患者血清ＰＲＬ＞２００μｇ／Ｌ。１０例垂体ＰＲＬ腺瘤出现了肿瘤钙化。结论：近年来垂体ＰＲＬ腺瘤的比例已逐渐升高，患者的早期内分泌症状、血清ＰＲＬ水平、影像学特征尤其是肿瘤钙化影像对垂体ＰＲＬ腺瘤的术前定性诊断有重要意义。
Objective: To study the changes of clinical characteristics in prolactinomas. Methods: Retrospective study has been done in 114 prolactinomas that were found in 382 patients with pituitary adenomas treated in our department among last ten years. Result: It was shown that the incidence of prolactinoma had elevated consistently among last ten years. In recent years, the complaints of endocrinal disorders were more common, but the symptoms of endocrinal disorders were still ignored in some patients. Serum prolactin levels were above 200μg/L in 60 2% of patients. Calcifications were found in 8 8% (10 cases) of prolactinomas. Conclusion: Prolactinomas were found in 44% patients with pituitary adenomas. The early symptoms of endocrinal disorders, serum prolactin level and the tumor calcifications in CT scan are very important for the pre operative diagnosis in patients with prolacinomas.
出处
《中华神经外科杂志》
CSCD
北大核心
1997年第2期73-75,共3页
Chinese Journal of Neurosurgery
