摘要
目的观察加巴喷丁抗癫癎作用的有效性与安全性。方法观察各种类型癫癎患者32例,以GBP用药前3个月平均发作频率为基线,与用药3个月后发作频率进行比较,观察疗效及不良反应。结果加巴喷丁对全面性发作治疗疗效优于部分性发作,新诊断癫癎有效率高于难治性癫癎。加巴喷丁不良事件发生率低且症状轻微。结论加巴喷丁对各种类型癫癎发作均有一定疗效,是一种安全性较好的药物。对全身性发作类型有效,对部分性发作疗效欠佳,对新诊断癫癎有效,难治性癫癎疗效欠佳。
Objective To observe the effectiveness and safety of gabapentin on epilepsy. Methods For 32 patients with various epilepsy, compared the average seizure frequency 3 months after using gabapentin to that 3 months before using it and observed gabapentin＇s effectiveness and safety. Results Gabapentin＇s effect on generalized seizure was prior to that on partial seizure, and the effect on newly diagnosed epilepsy was better than that on refractory epilepsy; the side effects of gabapentin occurred rarely and the symptoms were slight. Conclusion Gabapentin has a certain effect on various epilepsy, and it is a safe antiepileptic drug. Gabapentin has effect on generalized seizure and not so good on partial seizure, it has effect on newly diagnosed epilepsy, and not so good on refractory epilepsy.
出处
《中国实用神经疾病杂志》
2007年第7期31-32,共2页
Chinese Journal of Practical Nervous Diseases
关键词
加巴喷丁
癫癎
有效性
Gabapentin
Epilepsy
Effectiveness
