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Cyberknife——新一代放射外科设备 被引量:3

Cyberknife——the new radiotherapy equipment
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摘要 目的阐述射波刀(Cyberknife)的结构和特性以及临床应用初步体会。方法文献及射波刀相关资料回顾,结合我院射波刀临床应用初步体会进行讨论。结果射波刀是机器人投射、实时影像追踪定位、红光二极管同步追踪摄像机、自动化的治疗床、智能化的治疗计划系统、质量保证和质量控制6个子系统组成。射波刀开创性地应用非等中心、非共面、非聚焦的"三非"放疗模式,在靶区外半球面上有100个结点,1200条射束供治疗计划系统选用。革命性地应用骨骼结构作为参考框架实时影像追踪定位,确保了治疗精准度在亚毫米水平;创新性红光二极管同步呼吸追踪和XsightLung技术解决了体部肿瘤受呼吸运动影响的困扰;XsightSpine技术攻克脊柱病变的定位难题;智能化治疗计划系统具有强大运算功能,单/三路径的设计使治疗更加人性化。采用全新的大剂量单次或2~5低分次放疗模式治疗全身各部位肿瘤。结论射波刀是唯一兼容放射外科和放射治疗的新一代4D放疗设备,属于全新的放疗模式,使放射治疗进入4D时代。 Objective To introduce the architecture and principle of the Cyberknife Robotic Radiosurgery System,and the preliminary clinical experiences. Methods Reviewed literature references and related documents of the Cyberknife, and disussed preliminary experiences of the Cyberknife in our hospital. Results The CyberKnife consists of six sub-systems such as robotic delivery system, real-time image targeting system, and synchrony camera system, automatic treatment couch system, intelligent treatment planning system, Quality assurance and quality control system. The Cyberknife uses the "three-non"model of radiation treatment, non-isocenter, non-coplannarand non-focusing. More than 100 nodes are designed on the hemisphere around the treatment target, and 1200 beams can be chosen by the treatment planning system. Skeleton structures are used as the reference frame to perform internal target localization and real-time patient tracking. The patient tracking accuracy is maintained in sub-millimeter level during the entire treatment delivery. Innovative infrared camera synchronous tracking technology and Xsight technology to capture the body and spinal tumor localization problem. Single / 3 Paths design can provide more humane treatment. The Cyberknife is able to treat tumors all over the whole-body, using radiation treatment model of large dose single fraction, or 2-5 hypo-fractions. Conclusion Cyberknife Robotic Radiosurgery System is a new and revolutionary radiosurgery system, it is the brand-new 4D radiotherapy equipment which can compatible radiosurgery and radiotherapy, and expand radiation therapy into 4D period.
出处 《中国医学装备》 2007年第10期56-59,共4页 China Medical Equipment
关键词 射波刀 4D放射外科设备 实时影像跟踪定位 Cyberknife, 4D radiotherapy equipment, real-time image targeting
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参考文献6

  • 1[2]Yu C,Jozsef G,ApuzzoML,etal.Measurements of the relative output factors for CyberKnife collimators.Neurosurgery,2004,54(1):157-161.
  • 2[3]Kuo JS,Yu C,Petrovich Z,et al.The CyberKnife stereotactic radiosurgery "system:description,installation,and an initial evaluation of use and functionality.Neurosurgery",2003,53 (5):1235 -1239.
  • 3[4]lnoue T,lnoue T,Shiomi H,et al.Clinical experience of new stereotactic radiotherapy system named CyberKnife.Nippon Rinsho,2001.59(8):1624-1631.
  • 4[5]Chang SD,Adler JR.Robotics and radiosurgery"the cyberknife.Stereotact Funct Neurosurg,2001,76(3-4):204-208.
  • 5[6]King CR,Lehmann J,Adler JR,et al.CyberKnife radiotherap)for 1 ocalized prostate cancer:rationale and technical feasibility Teehnol Cancer Res Treat.2003,2(1):25-30.
  • 6韩俊庆,盛巍,刘奇.CyberKnife在肿瘤立体定向放射治疗中的应用[J].国外医学(肿瘤学分册),2004,31(12):901-904. 被引量:11

二级参考文献19

  • 1Chang SD, Main W, Martin DP, et al. An analysis of the accuracy of the CyberKnife:a robotic frameless stereotactic radiosurgical system.Neurosurgery,2003,52 ( 1 ): 140-146.
  • 2Shimamoto S, Inoue T, Shiomi H, et al. CyberKnife stereotactic irradiation for metastatic brain tumors. Radiat Med, 2002,20 ( 6 ): 299-304.
  • 3Park YG, Choi JY, Chang JW, et al. Gamma knife radiosurgery for metastatic brain tumor. Stereotact Funct Neurosurg,2001,76 ( 3 -4 ): 201-203.
  • 4Serizawa T,Ono J, lchi T, et al. Gamma knife radiosurgery for metastatic brain tumors from lung cancer:a comparison between small cell and non-small cell carcinoma. J Neurosurg,2002,97 (5 Suppl) :484-488.
  • 5Quinn AM. CyberKnife: a robotic radiosurgery system. Clin J Oncol Nurs,2002,6 ( 3 ): 149,156.
  • 6Inoue T, Inoue T, Shiomi H, et al. Clinical experience of new stereotactic radiotherapy system named CyberKnife. Nippon Rinsho,2001,59(8): 1624-1631.
  • 7Chang SD, Adler JR. Robotics and radiosurgery--the cyberknife. Stereotact Funct Neurosurg,2001,76 ( 3 -4 ): 204-208.
  • 8Shiomi H, Inoue T, Nakamura S, et al. Quality assurance for an imageguided frameless radiosurgery system using radiochromic film. Int J Radiat Med,2000,18(2) :107-113.
  • 9Yu C, Jozsef G, Apuzzo ML, et al. Measurements of the relative output factors for CyberKnife collimators. Neurosurgery, 2004,54 (1): 157-161.
  • 10Kuo JS, Yu C, Petrovich Z, et al. The CyberKnife stereotactic radiosurgery system: description, installation, and an initial evaluation of use and functionality. Neurosurgery,2003,53 (5) :1235-1239.

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