摘要
目的:观察初次由平原进入高原的30名健康青年男性的睡眠状况,分析高原睡眠紊乱与急性高山病的关系。方法:通过自身对照研究,30名健康青年男性在平原及高原进行多导睡眠监测(PSG),填写急性高山病(AMS)评分表。结果:高原睡眠时间显著减少(355.22±56.02minvs401.48±68.87min,P<0.01);睡眠期转换次数增加显著(71.51±12..60次vs53.17±15.47次,P<0.01);浅睡眠及觉醒显著增加(52.65±10.65%vs41.92±12.45%,P<0.01),(11.38±8.43次/hvs9.10±11.30次/h,P<0.01);深睡眠减少及快动眼睡眠显著减少(3.14±4.70%vs11.24±7.46%,P<0.01);出现周期性呼吸,夜间血氧饱和度及呼气末CO2显著下降(96.44±0.98%vs85.32±0.17%,P<0.01),(22.61±7.69mmHgvs33.13±7.85mmHg,P<0.01);觉醒指数、SaO2与AMS评分呈明显相关。结论:健康青年男性在初进高原时出现表浅、片断状睡眠,频繁周期性呼吸及严重的去氧饱和,睡眠质量下降,影响日间工作效率,睡眠紊乱与AMS的发生相关。
Objective：To investigate sleep in healthy young male who firstly go to high altitude from plain and analyze the relationships between high altitude sleep disorder and acute mountain sickness.Methods：Thirty subjects underwent polysomnography （PSG）and Lake Lusious score of acute mountain sickness on the plain and plateau respectively by auto-comparison study.Results：The thirty subjects had high altitude sleep disorders which manifested decreased total sleep time [355.22±56.02 （m） vs 401.48±68.87 （m）,P〈0.01],increased sleep-period interchange and superficial sleep and arouse [（71.51±12..60 vs 53.17±15.47,P〈0.01）; （52.65±10.65% vs 41.92±12.45% ,P〈0.01）; （11.38±8.43.h^-1 vs 9.10±11.30.h^-1,P〈0.01）],decreased deep sleep and rapid eye movement （REM）sleep （3.14±4.70% vs 11.24±7.46% ,P〈O.O1 ） ,periodic breathing （PB）was observed, significantly decreased oxygen saturation（SO2）and end-tidal carbon dioxide （ETCO2）[（96.44±0.98% vs 85.32±0.17%,P〈0.01）; （22.61±7.69mmHg vs 33.13±7.85mmHg,P〈0.01）].Acute mountain sickness （AMS）was significantly correlated with arousal index （AI）and arterial oxygen saturation （SaO2）.Conclusion：The healthy young people who go to plateau at the first time have light and intermittent sleepness,frequent PB and serious low SO2.Sleep quality is decreasing and it will affect working efficiency at day time.Sleep disorder is related to acute mountain sickness.
出处
《中日友好医院学报》
2007年第5期262-265,共4页
Journal of China-Japan Friendship Hospital
关键词
高原
睡眠紊乱
急性高山病
high altitude
sleep disorder
acute mountain sickness
