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自主呼吸在正压机械通气中的生理学效应 被引量：2

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摘要 对于呼吸衰竭患者，正压控制通气是改善其通气和换气功能的有效手段。但作为一种反生理的通气方式，正压控制通气不仅对呼吸和循环功能产生一定的负面影响，而且还会影响到胸外其他脏器。而最近大量临床和动物研究表明，若能在正压控制通气过程中保留一定程度的自主呼吸，将有助于改善呼吸、循环及其他脏器的功能，明显提高正压控制通气的疗效与安全性。
作者 夏金根 詹庆元
机构地区 首都医科大学附属北京朝阳医院-北京呼吸疾病研究所
出处 《中华结核和呼吸杂志》 CAS CSCD 北大核心 2007年第10期782-784,共3页 Chinese Journal of Tuberculosis and Respiratory Diseases
基金 北京市科技新星计划项目(2005B03)
关键词 正压机械通气 生理学效应 自主呼吸 控制通气 呼吸衰竭患者 循环功能 换气功能 通气方式
分类号 R459.6 [医药卫生—治疗学]
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参考文献20

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同被引文献19

  • 1丁素琴,罗爱林,马自成.依托咪酯对小儿肾上腺皮质激素含量的影响[J].同济医科大学学报,1994,23(5):383-385. 被引量：5
  • 2Esteban A, Anzueto A, Frutos F, et al. Characteristics and outcomes in adult patients receiving mechanical ventilation : a 28- day international study [ J ] . JAMA, 2002, 287 ( 3 ) : 345-355.
  • 3Tremblay LN, Slutsky AS. Ventilator-induced injury : from barotrauma to biotrauma [ J ] . Proc Assoc Am Physicians, 1998, 110 (6) : 482-488.
  • 4Slutsky AS, Tremblay LN. Multiple system organ failure. Is mechanical ventilation a contributing factor? [ J ] . Am J Respir Crit Care Med, 1998, 157 (6 Pt 1 ) : 1721-1725.
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  • 6The Acute Respiratory Distress Syndrome Network. Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome [ J ] . N EnglJ Med, 2000, 342 (18) : 1301-1308.
  • 7Villar J, Kacmarek RM, Perez-Mendez L, et al. A high positive end-expiratory pressure, low tidal volume ventilatory strategy improves outcome in persistent acute respiratory distress syndrome : a randomized, controlled trial [ J ]. Crit Care Med, 2006, 34 ( 5 ) : 1311-1318.
  • 8Rotstein C, Evans G, Born A, et al. Clinical practice guidelines for hospital-acquired pneumonia and ventilator-associated pneumonia in adults [ J ]. Can J Infect Dis Med Microbiol, 2008, 19 ( 1 ) : 19-53.
  • 9Torres A, Carlet J. Ventilator-associated pneumonia. European Task Force on ventilator-associated pneumonia [ J ] . Eur Respir J, 2001, 17 (5) : 1034-1045.
  • 10Dodek P, Keenan S, Cook D, et al. Evidence-based clinical practice guideline for the prevention of ventilator-associated pneumonia [ J ] . Ann Intern Med, 2004, lgl ( 4 ) : 305-313.

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中华结核和呼吸杂志
2007年 第10期

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