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不孕妇女子宫内膜组织学及酶组织化学研究

Studies on the Histological Features and Enzymatic Histochemical Changes of Endometrium in Infertile Women
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摘要 本文对36例不孕妇女及8例正常生育过的妇女进行子宫内膜组织学及酶组织化学检测。结果表明:不孕组子宫内膜腺上皮葡萄糖-6-磷酸脱氢酶(G-6-PD)活性积分均值明显低于对照组(P<0.01),其中6例G-6-PD完全缺失;酸性磷酸酶(ACP)、碱性磷酸酶(AKP)在两组间差异无显著性;两组间子宫内膜发育异常率比较差异无显著性(P>0.05);在不孕者中子宫内膜发育异常者G-6-PD活性明显低于发育正常者(P<0.05),且两者与对照组比较均差异有显著性(P<0.01),提示不孕妇女中部分存在子宫内膜G-6-PD缺失。 Histoloigical features of endometrium and their enzymatic activities in infenile women(n = 36) compared with that in women with normal fertility (n = 8)were studied by histologic and histochemical tests. The results showed that the activities of G - 6 - PD in infenile women were sinificantly lower than that in the nomal control (P<0.01 ). Activity defect of G - 6 - PD was observed in 6 of them. No difference was found in the activities of ACP and AKP of infertile women compared with controls (P >0. 05). There was also no significant difference in the incidence of retrded endometrial development in both groups (P >0.05). However, activities of G - 6 - PD in women with out of phase (OOP) were significanily lower than that in women with in phase (IP)(P<0.05). The results indicate that some infertile women may have activity defect of G - 6 - PD of endonetrium.
出处 《湖南医学》 1997年第3期129-131,共3页 Hunan Medical Journal
关键词 子宫内膜 葡萄 糖磷酸脱氢酶 女性 不育 infertility endometrium histology glucosephosphatedehydrogenase deficiency
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  • 1潘秀森,黄自强,谢志淳,王士贤,李志达,郭文璟.国产环硫雄醇的毒性、抗雌激素活性及其对小鼠乳腺癌的抑制作用[J]福建医学院学报,1987(04).
  • 2彭林,杨宜弟.炔诺酮肟对大鼠抗着床抗早孕作用机理的形态学研究[J]生殖与避孕,1986(01).
  • 3李和平,王迺功,雷海鹏.雌三醇的抗生育作用[J]生殖与避孕,1986(01).

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