摘要
本文对36例不孕妇女及8例正常生育过的妇女进行子宫内膜组织学及酶组织化学检测。结果表明:不孕组子宫内膜腺上皮葡萄糖-6-磷酸脱氢酶(G-6-PD)活性积分均值明显低于对照组(P<0.01),其中6例G-6-PD完全缺失;酸性磷酸酶(ACP)、碱性磷酸酶(AKP)在两组间差异无显著性;两组间子宫内膜发育异常率比较差异无显著性(P>0.05);在不孕者中子宫内膜发育异常者G-6-PD活性明显低于发育正常者(P<0.05),且两者与对照组比较均差异有显著性(P<0.01),提示不孕妇女中部分存在子宫内膜G-6-PD缺失。
Histoloigical features of endometrium and their enzymatic activities in infenile women(n = 36) compared with that in women with normal fertility (n = 8)were studied by histologic and histochemical tests. The results showed that the activities of G - 6 - PD in infenile women were sinificantly lower than that in the nomal control (P<0.01 ). Activity defect of G - 6 - PD was observed in 6 of them. No difference was found in the activities of ACP and AKP of infertile women compared with controls (P >0. 05). There was also no significant difference in the incidence of retrded endometrial development in both groups (P >0.05). However, activities of G - 6 - PD in women with out of phase (OOP) were significanily lower than that in women with in phase (IP)(P<0.05). The results indicate that some infertile women may have activity defect of G - 6 - PD of endonetrium.
出处
《湖南医学》
1997年第3期129-131,共3页
Hunan Medical Journal
关键词
子宫内膜
葡萄
糖磷酸脱氢酶
女性
不育
infertility
endometrium
histology
glucosephosphatedehydrogenase deficiency