摘要
目的研究骨量和松质骨显微结构的变化,及其与骨质疏松症骨折发生之间的关系。方法研究采用相对较为成熟的螺旋CT扫描三维重建,并借助工程学上的Euler定律,以活体无创三维成像方法,对小梁骨的结构和连接性进行观察和分析。结果随着年龄的增长,横向排列的骨小梁逐渐消失,纵向骨小梁变细,与周围的小梁逐步失去其连接性;二维横断面图像在小梁连接性描述上有一定的局限性,原因是小梁骨在垂直方向的走向并非规律有序。由于松质骨的显微结构具有不同的类型,它们之间不能等同比较。结论三维结构连接性和连接密度的结果显示板状型的小梁具有较高的连接密度和较小的连接性;而杆状型的小梁则连接密度较低和连接性较好。
Objective In our paper, the change of trabecular bone mass and microstructure and their relationship with the incidence of osteopenic fractrure were studied. Methods In this study, we used an advanced spiral CT scanner to perform a series of 3-D reconstruction of cancellous bone, and we investigated the architecture and connectivity of cancellous bone calculated by a Euler law with an implementation of noninvasive 3-D reconstruction in vivo. Results Results demonstrate that the transversal cancellous bone gradually disappears and the longitudinal one gets thinner as age increases. And the connectivity of cancellous bone is gradually lost. Images of 2-D transversal section may contribute to the connective depicting of cancellous bone to the limit, owing to irregular orientations in longitudinal cancellous bone. We could not simply make a comparison between the cancellous bone which have different microstructure patterns. Conclusions We found from the connectivity and density of 3-D reconstruction, that one case with a platelike structure has a relatively high density and relatively low connectivity, whereas the other case with a rod-like structure has a relatively low density and a relatively high connectivity.
出处
《中国骨质疏松杂志》
CAS
CSCD
2007年第1期29-32,共4页
Chinese Journal of Osteoporosis
关键词
小梁骨
骨结构
连接性
三维重建
骨质疏松
Cancellous bone
Bone structure
Connectivity
3-D reconstruction
Osteoporosis
