摘要
对150例病毒性肝炎病人采用免疲荧光抗体法进行了外周血 T 淋巴细胞亚群的检测,以30名健康人为对照,并探讨了该亚群与 ALT、HBV—M的关系。与对照组相比,AH、CPH、CAH、LC 组,除 LC 组 CD_8^+,AH 组 CD_4^+/CD_8^+外,CD_3^+、CD_4^+、CD_8^+、CD_4^+/CD_8^+均明显减少(P<0.01),但各临床分型闻无显著差异(P>0.05);ALT 50u 以下及以上组,除50u 以下组CD_8^+,51u 以上组 CD_4^+/CD_8^+外,CD_3^+、CD_4^+、CD_8^+、CD_4^+/CD_8^+均明显减少(P<0.01);CAH 的HBeAg(+)和(或)抗 HBcIgM(+)组、抗 HBs(+)和(或)抗 HBe(+)组只有 CD_3^+、CD_4^+明显减少(P<0.01),HBeAg(+)和(或)抗 HBcIgM(+)组 CD_4^+/CD_8^+减少(P<0.05)。
The peripheral blood T lymphocyte subgroups were detected by immunofluorescent antibody technique in 150 cases of viral hepatitis and in 30 heathy persons.The relationships between the T lymphocyte subgroups and ALT or HBV-M were discussed.As compared with the healthy persons,the levels of CD_3^+,CD_4^+,CD_8^+ and CD_4^+/CD_8^+ in the AH,CPH,CAH and LC group were decreased notably(P<0.01),but there were no significant difference among the clinical types(P<0.05);the levels of CD_3^+,CD_4^+ CD_8^+ and CD_4^+/CD_8^+ in ALT activity more or less than 50u/L groups were decreased obviously(P<0.01);the levels of CD_3^+ andCD_4^+ were decreased notably in HBeAg(+)and /or anti-HBclgM(+)group and in anti-HBs(+)and/or anti-HBe(+) group of CAH,the levels of CD_4^+/CD_~8+ were decreased in HBeAg(+)and/or anti- HBclgM(+)group(P<0.05).
出处
《承德医学院学报》
1997年第2期102-104,共3页
Journal of Chengde Medical University
关键词
病毒性肝炎
T淋巴细胞亚群
viral hepatitis
T lymphocyte subgroup
ALT
HBV-M
immunofluorescent antibody technique
