摘要
本文报道中药活血化瘀煎剂在临床与实验室证实可阻止溶血的基础上，为探讨其作用机制，对G6PD缺乏与G6PD正常新生儿进行治疗前后G6PD／6PGD比值对比观察，结果活血化瘀煎剂服后均可使G6PD缺乏者G6PD／6PDD比值增高，甚至达正常，而G6PD正常者服后比值不变，提示活血化瘀煎剂作用机制可能基于强大之抗氧化作用及抗骨髓休克、活跃生血，促进G6PD之生成，甚至纠正其缺乏，而不仅是替代作用。为开发此方剂作为广泛防治G6PD缺乏病儿，提供了科学依据。
A traditional medicine drug named HuoXueHuaYu with the actions of invigorate the circulation of blood and dispersing extravasated blood,which is identified by clinic and laboratory to prevent hemolysis, is reported in this paper. In order to study its mechanism, the ratio of G6PD/6PGD in neonates with G6PD deficiency and normal G6PD is observed before and after treatment with the drug. The results shows the ratio of G6PD/6PGD in G6PD deficiencier rises, even to normal after administration of the drug, however the ratio remains unchanged in neonates with normal G6PD. This suggests the mechanism of the drug may be strong antioxygenation, anti-bone marrow shock, hemogenesis, promoting synthesis of G6PD, even correcting the deficiency. The study provides scientific evidence for widely using of this Chinese Medicine drug in treatment of patients with G6PD deficieney.
出处
《中国优生与遗传杂志》
1997年第2期85-86,88,共3页
Chinese Journal of Birth Health & Heredity
关键词
活血化瘀
G6PD缺乏症
新生儿
中医药疗法
G6PD deficieney, Ratio of G6PD/6PGD, Traditional medicine, Drug HuoxueHuayu
