摘要
库欣综合征患者往往伴有一系列全身性代谢合并症如中心性肥胖、高血压、胰岛素抵抗、糖代谢异常、血脂紊乱、血液高凝状态等。这些表现均为代谢综合征的特征,也是重要的心血管疾病危险因素。库欣综合征与代谢综合征联系密切,可以作为研究代谢综合征的模型。库欣综合征患者治愈、皮质醇水平恢复正常后仍有可能存在与疾病活动期类似的代谢紊乱和心血管疾病危险因素。
Cushing＇s syndrome is characterized by a series of systemic complications, including abdominal obesity, hypertension, insulin resistance, impairment of glucose metabolism, dyslipidemia, hypercoagulabale state, etc. These characteristics are features of metabolic syndrome, which also are important cardiovascular risk factors. As a useful model for the research of metabolic syndrome, Cushing＇s syndrome has a close relationship with it. The remission or normalization of circulating cortisol levels of patients with Cushing＇s syndrome is not always followed by completely disappearance of metabolic disorder and cardiovascular risk factors which existed in the active phase of the disease.
出处
《国际内分泌代谢杂志》
2007年第5期345-347,共3页
International Journal of Endocrinology and Metabolism
关键词
库欣综合征
心血管疾病
危险因素
代谢综合征
Cushing＇s syndrome
Cardiovascular disease
Risk factors
Metabolic syndrome
