期刊文献+

苍耳子风湿药酒的研制与检测 被引量:3

Development and Determination of Fengshi Medical Wine of Fructus xanthii
在线阅读 下载PDF
导出
摘要 实验确定了回流提取法为苍耳子药酒生产的最佳工艺,建立苍耳子风湿药酒的质量标准,利用高效液相色谱法检测苍耳子有效成分绿原酸。绿原酸进样量在0.315~1.575μg范围内呈良好的线性关系,回归方程为Y=1857900X+7575.80,r=0.999985(n=5),平均加样回收率为99.22%,RSD值为1.38%(n=6)。结果表明本方法简便、快速、灵敏、准确、重复性好,可以控制苍耳子风湿药酒的质量。 Experimentntal results inchicated that the optimal production method of Fengshi medical wine of Fructus xanthii was circumfluence extraction. An RP-HPLC method was established for determination of chloralgenic acid in Fengshi medical wine of Fructus xanthii. The calibration curve was in good linearity over the range of 0.315 - 1.575 tag with the regression equation Y=1857900X+7575.80, r=-0.999985(n=5). The average recovery was 99.22% with RSD=-1.38%(n=6). The method appeared to be simple, accurate, reproducible and could be used to control the quality of Fengshi medical wine of Fructus xanthii.
出处 《食品科学》 EI CAS CSCD 北大核心 2007年第9期481-484,共4页 Food Science
基金 吉林工程技术师范学院大学生创新基金项目
关键词 苍耳子 风湿药酒 高效液相色谱 Fructus xanthii Fengshi medical wine HPLC
  • 相关文献

参考文献6

二级参考文献22

  • 1李涓,高天,谢子清,唐熠.苍耳子不同提取物的毒性比较实验[J].时珍国医国药,2005,16(6):484-487. 被引量:15
  • 2Yoshizaki K, Nishimoto N, Mihara M, et al. Therapy of rheumatoid arthritis by blocking Il-6 signal transduction with a humanized anti-IL-6 receptor antibody[J]. Springer Semin Immunopathol, 1998, 20(2): 247-259.
  • 3Schett G, Tohidast-Akrad M, Smolen JS, et al. Activation, differential localization, and regulation of the stress-activated protein kinases, extracellular signal-regulated kinase, c-JUN N-terminal kinase, and p38 mitogen-activated protein kinase, in synovial tissue and cells in rheumatoid arthritis[J]. Arthritis Rheum, 2000, 43(9): 2501-2512.
  • 4Han Z, Boyle DL, Chang L, et al. c-Jun N-terminal kinase is required for metalloproteinase expression and joint destruction in inflammatory arthritis[J]. J Clin Invest, 2001, 108(1): 73-81.
  • 5Shiozawa S, Shimizu K, Tanaka K, et al. Studies on the contribution of c-fos/AP-1 to arthritic joint destruction[J]. J Clin Invest, 1997, 99(6): 1210-1216.
  • 6Vanderbark AA, Morgan E, Bartholomew R, et al. TCR peptide therapy in human autoimmune disease[J]. Neurochem Res, 2001, 26(6): 713-773.
  • 7Gracie JA, Forsey RJ, Chan WL, et al. A proinflammatory role for IL-18 in rheumatoid arthritis[J]. J Clin Invest, 1999, 104(10): 1393-1401.
  • 8Gary SF. Evolving concepts of rheumatoid arthritis[J]. Nature, 2003, 423: 356-361.
  • 9Pap T, Aupperle KR, Gay S, et al. Invasiveness of synovial fibroblasts is regulated by p53 in the SCID mouse in vivo model of cartilage invasion[J]. Arthritis Rheum, 2001, 44(4): 676-681.
  • 10Sen M, Chamorro M, Reifert J, et al. Blockade of Wnt-5A/Frizzled 5 signaling inhibits rheumatoid synoviocyte activation[J]. Arthritis Rheum, 2001, 44(4): 772-781.

共引文献94

同被引文献52

引证文献3

二级引证文献28

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部