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舒芬太尼在非体外循环下冠状动脉旁路血管移植术的应用 被引量:3

Clinical Application of Sufentanil in Patients Underwent Off-Pump Coronary Artery Bypass Grafting
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摘要 目的:通过对芬太尼和舒芬太尼应用于冠状动脉旁路血管移植术(OPCABG)的安全性、术后清醒时间和拔除气管导管时间的比较,了解舒芬太尼对于OPCABG是否较芬太尼更具优势。方法:拟择期行OPCABG病人40例,年龄40~70岁,体重50~90kg,美国麻醉医师协会(ASA)病情分级Ⅱ~Ⅲ级,随机分为舒芬太尼组(观察组,n=20)和芬太尼组(对照组,n=20)。2组均记录手术时间、术后清醒时间、气管导管拔除时间。结果:2组病人术中血流动力学变化平稳且相似,但清醒时间和气管导管拔除时间差异具有显著性意义。结论:舒芬太尼用于OPCABG安全平稳,术后病人清醒时间和气管导管拔除时间均明显短于芬太尼组,可作为快通道麻醉的首选药物之一。 Objective: Abstract: Objective: The aim of this study was to investigate the hemodynamic effects of Sufentanil-based and Fentanyl-based technique for Off-Pump Coronary Artery Bypass Grafting (OPCABG) , through safety, extubation time and awake time to understand if Sufentanil is better than Fentanyl. Methods:40 patients underwent OPCABG,with ages from 40 - 70 years, body weight 50 - 90 kg, ASA Ⅱ-Ⅲ grade were randomly divided into Sufentanil group (n = 20) and Fentanyl group (n = 20). Operation time,extubation time and awake time were recorded. Results:Dynamic changes in blood flow and clinical characteristics were similar between the two groups. All patients were safely transferred to ICU,and extubated after awake without're-extubation. Hemodynamic stability was obtained in both groups. There was significant difference in extubation time and awake time between the two groups,they were much shorter in Sufentanil group. Conclusion: Sufentanil has some advantage in OPCABG,it can be choosed first in fast track anesthesia.
出处 《临床误诊误治》 2007年第9期3-4,5,共3页 Clinical Misdiagnosis & Mistherapy
关键词 冠状动脉旁路移植术 非体外循环 舒芬太尼 镇痛药 阿片类 临床研究 Coronary artery bypass grafting, Off-pump Sufentanil Analgesics, opioid Clinical research
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