摘要
目的研究上海地区阿罗格皮肤点刺试验阳性病例在变应原分布、年龄、季节等方面的特点。方法应用阿罗格点刺试液对上海地区1000例有鼻部过敏症状者进行皮肤点刺试验，分析30种变应原的分布以及在不同季节的阳性率。按年龄将1000例被调查者分为≤17岁、18～39岁、40～59岁和≥60岁组，分别计算皮肤点刺试验阳性率，并进行统计学处理。结果皮肤点刺试验的阳性率，30种变应原中以粉尘螨、屋尘螨最高，其次为干草尘埃、胶乳、狗上皮、猫上皮；男女之间差异无统计学差异（P〉0．05）；秋、冬季显著高于春、夏季（P〈0．01）；随着年龄的增大，阳性率呈阶梯式下降趋势（P〈0．01）。结论上海地区变应性鼻炎患者的变应原以粉尘螨、屋尘螨为主；点刺试验阳性率以秋、冬季较高且随年龄的增大呈下降趋势。
Objective To investigate the clinical feature of distributions of allergens, age and season in patients accepting allergopharma skin prick test （ASPT） in shanghai. Methods One thousand patients with nasal hypersensitivity were included in the study and performed ASPT. The distribution of 30 allergens and positive rate among different seasons were analysed. All the patients were divided into four groups according to ages ： ≤ 17 years old, 18 to 39, 40 to 59, and ≥ 60. The positive rate of ASPT were calculated for the groups, and statistical analysis was conducted. Results Dermatophagoides farinae （Der f） and Dermatophagoides pteronyssinus （Der p） were the most common allergens, followed by hay dust, rubber latex, dog epidermis and cat epidermis. There was no significant difference between male and female patients （ P 〉 0.05 ）. The positive rate for autumn and winter was higher than that for spring and summer （ P 〈 0.01 ）. The positive rate descended with the age increase （P 〈 0.01 ）. Conclusion In Shanghai Der f and Der p may be the most common allergens, the positive rate in ASPT for autumn and winter may be higher than that for spring and summer and may descend with the age.
出处
《上海交通大学学报（医学版）》
CAS
CSCD
北大核心
2007年第9期1075-1077,共3页
Journal of Shanghai Jiao tong University:Medical Science
