摘要
目的评估自制的下腔静脉滤器(DDIVCF)捕获猪血栓子的效果及其定位稳定性。方法①将DDIVCF滤器和进口Antheor临时性下腔静脉滤器分别置入于直径为20和25mm的下腔静脉(IVC)血液循环模型中,观察模型处于水平位时滤器对3mm×20mm,3mm×30mm,6mm×20mm,6mm×30mm4种大小不同的猪血栓子的捕获效果,并计算其捕获率。②测量滤器捕获大量6mm×30mm栓子后相对位移的距离,观察滤器的定位稳定性。结果①DDIVCF滤器在直径20和25mm的IVC模型中对4种猪血栓子的捕获率分别为34%,56%,82%,94%和26%,38%,56%,86%;Antheor的捕获率分别为54%,64%,86%,96%和38%,44%,68%,90%。对3mm×30mm,6mm×20mm,6mm×30mm猪血栓子的捕获率两者间差异无统计学意义(P>0.05)。②在直径20和25mm的IVC模型中DDIVCF滤器捕获猪血栓子后相对位移距离分别为(0.6±0.3)cm和(1.0±0.1)cm。Antheor的相对位移距离分别为(0.4±0.1)cm和(0.8±0.3)cm,两者差异无统计学意义(P>0.05)。结论DDIVCF在体外模型实验中具有较高的血栓捕获率和定位稳定性,可与进口Antheor临时性下腔静脉滤器媲美,其体内应用情况尚需进一步动物实验研究。
Objective To evaluate clot capturing efficacy and stability of a new domestic designed inferior vena cava filter（DDIVCF） by comparing with Antheor temporary vena cava filter in vitro. Methods （1）The DDIVCF and Antheor filter were tested in a flow model simulated the inferior vena cava（IVC） with 20 mm and 25 mm in diameter. The swine clots of four sizes were used ： 3 mm ×20 mm, 3 mm ×30 mm, 6 mm ×20 mm, 6 mm ×30 mm .The clot capturing capacity was observed in horizontal position. （2） The stability was observed by measuring the comparative moving distance of 6 mm × 30 mm clots after clot trapping. Results （1） DDIVCF capture rates were 34%, 56%, 82%, 94% and 26%, 38%, 56%, 86% for the 20 mm and 25 mm IVC models of four different sizes clots respectively, comparing with 54%, 6d%, 86%, 96% and 38%, 44%, 68%, 90%espectively of Antheor temporary vena cava filter. The capture rates of DDIVCF and Antheor filter showed no suificant differences of 3 mm ×30 mm, 6mm × 20 mm and 6 mm ×30 mm clots in 20 mm and 25 mm IVC models（P 〉 0.05）. （2） There was a few caudal migration with no significant difference （P 〉 0.05）. The filter migration distances were （0.6 ±0.3） cm and （1.0 ±0.1） cm respectively in the 20 mm and 25 mm IVC models with most clots of 6 mm ×30 mm were captured, comparing with （0.4 ±0.1 ） cm and （0.8 ±0.3） cm respectively for Antheor filter. Conclusions DDIVCF is a stable and effective filter in an in-vitro model experiment but application in vivo would rather be further evaluated through more animal experiments. （J Intervent Radiol, 2007, 16.. 260-263）
出处
《介入放射学杂志》
CSCD
2007年第4期260-263,共4页
Journal of Interventional Radiology
基金
江苏省科学技术发展(社会发展)基金资助项目(BS2003004)
南京市医学科技发展项目(ZKX0213)
关键词
下腔静脉
滤器
实验
体外
Inferior vena cava
Fiher
Experiment,in vitro
