摘要
目的用显微外科技术治疗复发性翼状胬肉,同时比较角膜缘干细胞移植联合丝裂霉素C(mitomycin C,MMC)治疗复发性翼状胬肉的临床疗效。方法将62例(67眼)患者随机分为2组,治疗组采用角膜缘干细胞移植联合应用丝裂霉素C,共34例(38眼);对照组单纯采用角膜缘干细胞移植技术,共28例(29眼),术后随访6～30个月。结果治疗组1眼复发,复发率2.63%,对照组3眼复发,复发率10.34%,两组比较差异有统计学意义(P<0.05),角膜创面上皮平均愈合时间治疗组为(6.61±1.79)d,对照组为(5.83±1.91)d,两组比较差异无统计学意义(P>0.05)。结论角膜缘干细胞移植术联合应用丝裂霉素C治疗复发性翼状胬肉再复发率低,未发生不良并发症,为治疗复发性翼状胬状安全和有效的手术方法。
Objective To compare the therapeutic effects of recurrent pterygium treated by microsurgical management. Methods Sixty-two cases （67 eyes） with recurrent pterygiumwere randomly divided into limbal stem cell autograft transplantation comblined with mitomycin C （34 cases, 38 eyes） and limbal stem cell autograft transplantation（28 cases, 29 eyes）. The post operative follow-up period was 6 to 30 months. Results One eye recurrence was noted in the trial group, the recurrent rate was 2. 63%. Three eyes recurrence was noted in the control group, the recurrent rate was 10. 34%. There was statistical significant difference between two groups （P 〈 0. 05 ）. The average epithelial recovering time of corneal wound was （6. 61 ± 1.79 ） days and （5.83 ± 1.91 ） days in two groups, the difference was not significant （P 〉 0. 05 ）. Conclusion Limbal stem cells autograft transplantation combined with mitomycin C can decrease the recurrent rate. It is an ideal methods of recurrent pterygium surgical procedure, is worth spreading.
出处
《中华显微外科杂志》
CSCD
北大核心
2007年第4期274-276,共3页
Chinese Journal of Microsurgery
