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腭成形术对人工腭裂大白鼠上颌骨发育影响的研究 被引量:4

STUDY OF AFFECTION ON MAXILLAR GROWTH IN ARTIFICER CLEFT PALATE OF RAT AFTER PALATE SURGERY
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摘要 以鼠龄为28~35天的幼年大白鼠建立人工腭裂模型后,经改良的Langenbeck’s法行腭裂成形术,于鼠龄为75~80天成年期处死动物,X线头颅测量结果显示手术修复组SNA角、ANB角的角度和S-A、I-Pm、N-A和Zyg-Zyg距离均明显减小,与正常组和未手术修复组相比都有高度显著性差异(P<0.01),说明实验组上颌骨前后径、垂直向和水平向均发育不良;根据本实验结果,我们认为幼年时行腭成形术明显影响上颌骨的正常发育,松驰切口区瘢痕形成是其重要的生物学基础之一。 The purpose of this article is to study whether the maxillary development is or not effected by palate surgery in artificial cleft palate of rats. The artificial palate cleft model was made in rats aged of 28-35 days, then the palate surgery was performed on with modificatory Langenbeck’s method. The animals were killed on aged of 75-80 days postoperatively. The cephalographic X-ray was taken and analyzed.The SNA and ANB angle are smaller and distance of S-A,I-Pm, N-A and Zyg-Zyg are shorter in experimental group than those of normal and contrast ones (P<0.01).The results show that the sagital, vertical and horizontal size of maxilla are undevelopment in experimental group. We believe that the maxilla development will be influenced by palate surgery when operated in younger child. The formation of scar at laxing incision area is one of the most important biological facts.
出处 《口腔颌面外科杂志》 CAS 1997年第1期20-23,共4页 Journal of Oral and Maxillofacial Surgery
关键词 腭成形术 腭裂 上颌骨 发育 动物实验 Palate surgery Palate cleft Maxilla Rat.
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