摘要
本文通过对2800m，4480m高原鼠兔和大白鼠肺表面活性物质的自身调节的研究。我们发现：大白鼠从兰州移居到3600m（天峻）后肺灌洗液中的磷脂含量都有不同程度的下降。蛋白质含量未见明显的变化。二个海拔高度的鼠兔肺磷脂含量均高于大白鼠，蛋白质含量略高于大白鼠。结果提示，天白鼠卵磷脂含量在缺氧时代偿性增加和其它磷脂成分下降，可能是卵磷脂合成代谢支路代偿活跃，在缺氧情况下磷脂合成供能方式发生适应性变化。高原鼠兔保持了土生动物高原适应性限速代谢和调节，保持自身呼吸状态稳定。这也许又是鼠兔自力生存的优势。
The Pulmonary surfaotant of plateau pika and rats were studied at 2 800m and 4 480m altitudes. We found that the multi -phospholipids were decreased in the lung of rats migrated to 3 600m altitude from Lan Zhou city,but the contents of protein did not change remarkably. The phospholipids as well as high protein in pike were higher than in rats at two various altitudes. The results suggest that the increase of lecithin and the decrease of other components of phospholipids anabolism and the active compensation of lecithin anabolism to high altitude hypoxia. lt could be an advantage for the pika adapted to high altitude environment.
出处
《高原医学杂志》
CAS
1997年第1期27-29,共3页
Journal of High Altitude Medicine
关键词
高原医学
高原
适应
肺表面活性物质
Hypoxia
Adaptation
Pulmonary surfactant
Phispholipids
Protein
