摘要
目的:探讨血清尿酸(UA)水平与冠心病(CHD)及其相关因素关系。方法:选择经冠状动脉造影检查证实的冠心病患者187例,冠脉造影正常对照组71例,常规空腹采集静脉血测定血清UA,分析冠心病危险因子、冠状动脉病变程度、病变支数及病变类型与相应UA水平的关系。结果:CHD组的一般资料与对照组无明显差异,但血清UA水平明显高于对照组(P<0.01);在CHD组中,轻度狭窄、中度狭窄及重度狭窄,其UA水平逐渐增高,分别为(418.92±36.52),(450.84±48.65),(487.40±51.62)μmol/L(P<0.01);单支病变、双支病变和三支病变,其UA水平也增高,分别为(426.32±30.78),(455.24±35.34),(480.40±40.12)μmol/L(P<0.01);A、B和C型病变,其UA水平依次增高,分别为(425.85±35.71),(461.65±46.50),(493.41±53.24)μmol/L(P<0.01);结论:血清UA水平的增高与冠心病密切相关,是冠心病发病的危险因素。
Objective：To study the relationship between serum uric acid（UA）and coronary heart disease（CHD）and its risk factors.Methods：187 CHD patients who had been identified by coronary arteriongraphy and 71 healthy people whose coronary arteries were normal by coronary arteriongraphy were enrolled in this trial.The level of serum UA of all subjects was examined under empty stomach.The correlations between UA and CHD risk factors,degree of coronary stenosis,number of involved coronary arterial trees and disease type were analyzed.Methods：The level of serum UA of CHD group was very significantly higher than that of the control group（P〈0.01）.In CHD group,the higher the level of serum UA was,the more stenosis the coronary artery was;when the number of involved coronary arterial trees was one,two and three,the level of serum UA was 426.32±30.78,455.24±35.34 and 480.40±40.12 umol/L,respectively;the level of serum UA of type A,type B and type C of the patients was 425.85±35.71,461.65±46.50 and 493.41±53.24 umol/L.Conclusion：The elevation of serum UA is correlated with development of CHD and is one of risk factor of CHD.
出处
《西南国防医药》
CAS
2007年第4期405-407,共3页
Medical Journal of National Defending Forces in Southwest China
关键词
冠心病
血清尿酸
危险因子
coronary heart disease,uric acid,risk factor
